FAT/CD36 participation in human skeletal muscle lipid metabolism: a systematic review

A Ramos-Jimenez, RA Zavala-Lira… - Journal of Clinical …, 2022 - mdpi.com
Fatty acid translocase/cluster of differentiation 36 (FAT/CD36) is a multifunctional membrane
protein activated by a high-fat diet, physical exercise, fatty acids (FAs), leptin, and insulin …

A dual mechanism of action for skeletal muscle FAT/CD36 during exercise

BK Smith, A Bonen, GP Holloway - Exercise and sport sciences …, 2012 - journals.lww.com
During exercise, muscle contraction requires a high demand for energy (adenosine
triphosphate (ATP)). The increase in substrate oxidation during exercise endeavors to match …

Association between “cluster of differentiation 36 (CD36)” and adipose tissue lipolysis during exercise training: A systematic review

EM El Ouali, L Bosquet, B Elgharbaoui, F Laziri… - Frontiers in …, 2023 - frontiersin.org
Fatty acid translocase (FAT/CD36) is a transmembrane glycoprotein belonging to the
scavenger class B receptor family and is encoded by the cluster of differentiation 36 (CD36) …

A null mutation in skeletal muscle FAT/CD36 reveals its essential role in insulin-and AICAR-stimulated fatty acid metabolism

A Bonen, XX Han, DDJ Habets… - American Journal …, 2007 - journals.physiology.org
Fatty acid translocase (FAT)/CD36 is involved in regulating the uptake of long-chain fatty
acids into muscle cells. However, the contribution of FAT/CD36 to fatty acid metabolism …

The fatty acid transporter FAT/CD36 is upregulated in subcutaneous and visceral adipose tissues in human obesity and type 2 diabetes

A Bonen, NN Tandon, JFC Glatz, J Luiken… - International journal of …, 2006 - nature.com
Background: Long-chain fatty acids (LCFAs) cross the plasma membrane via a protein-
mediated mechanism involving one or more LCFA-binding proteins. Among these …

Muscle-specific overexpression of FAT/CD36 enhances fatty acid oxidation by contracting muscle, reduces plasma triglycerides and fatty acids, and increases plasma …

A Ibrahimi, A Bonen, WD Blinn, T Hajri, X Li… - Journal of Biological …, 1999 - ASBMB
Increasing evidence has implicated the membrane protein CD36 (FAT) in binding and
transport of long chain fatty acids (FA). To determine the physiological role of CD36, we …

A novel function for fatty acid translocase (FAT)/CD36: involvement in long chain fatty acid transfer into the mitochondria

SE Campbell, NN Tandon, G Woldegiorgis… - Journal of Biological …, 2004 - ASBMB
Fatty acid translocase (FAT)/CD36 is a long chain fatty acid transporter present at the
plasma membrane, as well as in intracellular pools of skeletal muscle. In this study, we …

Differential Roles of CD36 in Regulating Muscle Insulin Response Depend on Palmitic Acid Load

J Sun, Y Su, J Chen, D Qin, Y Xu, H Chu, T Lu, J Dong… - Biomedicines, 2023 - mdpi.com
The possible role of fatty acid translocase (CD36) in the treatment of obesity has gained
increasing research interest since researchers recognized its coordinated function in fatty …

Regulation of fatty acid transport by fatty acid translocase/CD36

A Bonen, SE Campbell, CR Benton… - Proceedings of the …, 2004 - cambridge.org
Fatty acid (FA) translocase (FAT)/CD36 is a key protein involved in regulating the uptake of
FA across the plasma membrane in heart and skeletal muscle. A null mutation of FAT/CD36 …

FAT/CD36 regulates PEPCK expression in adipose tissue

Z Wan, S Matravadia, GP Holloway… - American Journal of …, 2013 - journals.physiology.org
Fatty acid translocase (FAT)/CD36 has been extensively studied for its role in facilitating fatty
acid uptake. Recent findings have also demonstrated that this protein regulates adipocyte …