Replication and assembly of human papillomaviruses

MJ Conway, C Meyers - Journal of dental research, 2009 - journals.sagepub.com
Human papillomaviruses (HPVs) are small dsDNA tumor viruses, which are the etiologic
agents of most cervical cancers and are associated with a growing percentage of …

Papillomavirus infectious pathways: a comparison of systems

J Biryukov, C Meyers - Viruses, 2015 - mdpi.com
The HPV viral lifecycle is tightly linked to the host cell differentiation, causing difficulty in
growing virions in culture. A system that bypasses the need for differentiating epithelium has …

Production of infectious human papillomavirus independently of viral replication and epithelial cell differentiation

D Pyeon, PF Lambert… - Proceedings of the …, 2005 - National Acad Sciences
Papillomaviruses are small DNA viruses that are associated with benign and malignant
epithelial lesions, including> 95% of cervical cancers and≈ 20% of head and neck cancers …

Arrangement of L2 within the papillomavirus capsid

CB Buck, N Cheng, CD Thompson, DR Lowy… - Journal of …, 2008 - Am Soc Microbiol
Papillomaviruses are a family of nonenveloped DNA tumor viruses. Some sexually
transmitted human papillomavirus (HPV) types, including HPV type 16 (HPV16), cause …

[HTML][HTML] In vitro papillomavirus capsid assembly analyzed by light scattering

GL Casini, D Graham, D Heine, RL Garcea, DT Wu - Virology, 2004 - Elsevier
Pentamers of the L1 major capsid protein of human papillomavirus (HPV type 11) were
purified after expression in E. coli and analyzed for the kinetics of in vitro capsid self …

Interaction of human papillomavirus (HPV) type 16 capsid proteins with HPV DNA requires an intact L2 N-terminal sequence

J Zhou, XY Sun, K Louis, IH Frazer - Journal of virology, 1994 - Am Soc Microbiol
Encapsidation of papillomavirus DNA involves DNA-protein and protein-protein interactions.
We sought to define the role of each human papillomavirus (HPV) capsid protein in HPV …

Papillomavirus virus-like particles as vehicles for the delivery of epitopes or genes

YF Xu, YQ Zhang, XM Xu, GX Song - Archives of virology, 2006 - Springer
Papillomaviruses (PVs) are simple double-strand DNA viruses whose virion shells are T= 7
icosahedrons and composed of major capsid protein L1 and minor capsid protein L2. L1 …

Self-assembly of human papillomavirus type 1 capsids by expression of the L1 protein alone or by coexpression of the L1 and L2 capsid proteins

ME Hagensee, N Yaegashi, DA Galloway - Journal of virology, 1993 - Am Soc Microbiol
Vaccinia virus vectors were used to express the major (L1) and minor (L2) capsid proteins of
human papillomavirus type 1 (HPV-1) with the vaccinia virus early (p7. 5K) or late (pSynth …

Generation of HPV pseudovirions using transfection and their use in neutralization assays

CB Buck, DV Pastrana, DR Lowy, JT Schiller - … : Methods and Protocols, 2006 - Springer
It has recently become possible to generate high-titer papillomavirus-based gene-transfer
vectors. The vectors, also known as papillomavirus pseudoviruses (PsV), have been useful …

Papillomavirus particles assembled in 293TT cells are infectious in vivo

TD Culp, NM Cladel, KK Balogh, LR Budgeon… - Journal of …, 2006 - Am Soc Microbiol
Papillomaviruses (PVs) demonstrate both tissue and species tropisms. Because PVs
replicate only in terminally differentiating epithelium, the recent production of infectious PV …