The contribution of B cells to the pathogenesis of relapsing-remitting multiple sclerosis
(RRMS) is currently of great interest due to the positive outcomes of treatment with B cell …

In this study we aimed to investigate whether treatment with an immune modulatory drug
had an effect on the distribution of B cell subpopulations in patients with remitting–relapsing …

Background There is accumulating evidence from immunological, pathological and
therapeutic studies that B cells are key components in the pathophysiology of multiple …

Objectives B cells are important in the pathogenesis of multiple sclerosis. It is yet unknown
which subsets may be involved, but atypical B cells have been proposed as mediators of …

Recent evidence suggests that B‐and T‐cell interactions may be paramount in relapsing‐
remitting MS (RRMS) disease pathogenesis. We hypothesized that memory B‐cell pools …

In the present study we showed that transitional B cells of patients with clinically isolated
syndrome (CIS) and relapsing–remitting multiple sclerosis (RR–MS) are reduced in the …

Introduction B cells are attracting increasing attention in the pathogenesis of multiple
sclerosis (MS). B cell-targeted therapies with monoclonal antibodies or plasmapheresis …

B cell subsets in newly diagnosed untreated, relapsing–remitting multiple sclerosis (MS)
patients were examined. The fraction of CD20+ B cells was significantly increased in MS …

In multiple sclerosis (MS), lymphocyte—in particular B cell—transit between the central
nervous system (CNS) and periphery may contribute to the maintenance of active disease …

Objective Results from anti‐CD20 therapies demonstrate that B‐and T‐cell interaction is a
major driver of multiple sclerosis (MS). The local presence of B‐cell follicle‐like structures …