Progesterone receptor membrane component 1 (PGRMC1) is a trans-membrane
evolutionarily conserved protein with a cytochrome b5 like heme/steroid binding domain …

Tumorigenesis requires the concerted action of multiple pathways, including pathways that
stimulate proliferation and increase metabolism. Progesterone receptor membrane …

Cancer is one of the leading causes of death in America, and there is an urgent need for
new therapeutic approaches. The progesterone receptor membrane component 1 …

Hormone signaling is important in a number of disease states, and hormone receptors are
effective therapeutic targets. PGRMC1 (progesterone receptor membrane component 1) is a …

Progesterone receptor membrane component 1 (PGRMC1) is a multi-functional protein with
a heme-binding moiety related to that of cytochrome b 5, which is a putative progesterone …

Cancer is one of the leading causes of death, and there is an urgent need for new
biomarkers and therapeutic targets. The progesterone receptor membrane component 1 …

Background Increased expression of the progesterone receptor membrane component 1
(PGRMC1) has been linked to multiple cancers, including breast cancer. Despite being a …

Progesterone receptor membrane component (PGRMC) proteins play important roles in
tumor growth, progression, and chemoresistance, of which PGRMC1 is the best …

Abstract Background Progesterone Receptor Membrane Component 1 (PGRMC1) is
expressed in many cancer cells, where it is associated with detrimental patient outcomes. It …

Simple Summary Ovarian and endometrial cancers occur frequently and can be lethal.
Recently, progesterone receptor membrane component (PGRMC) 1 and PGRMC2 have …