Evidence for a genomic mechanism of action for progesterone receptor membrane component-1
JJ Peluso, J DeCerbo, V Lodde - Steroids, 2012 - Elsevier
Progesterone receptor membrane component 1 (PGRMC1) is highly expressed in the
granulosa and luteal cells of rodent and primate ovaries. Interestingly, its molecular weight …
granulosa and luteal cells of rodent and primate ovaries. Interestingly, its molecular weight …
PGRMC1 is a novel potential tumor biomarker of human renal cell carcinoma based on quantitative proteomic and integrative biological assessments
D Zhang, X Xia, X Wang, P Zhang, W Lu, Y Yu, S Deng… - PloS one, 2017 - journals.plos.org
Progesterone receptor membrane component 1 (PGRMC1) is widely observed with an
elevated level in multiple human cancers. However, the roles of PGRMC1 in renal cancer …
elevated level in multiple human cancers. However, the roles of PGRMC1 in renal cancer …
PGRMC1 contributes to doxorubicin-induced chemoresistance in MES-SA uterine sarcoma
ST Lin, EWS May, JF Chang, RY Hu, LHC Wang… - Cellular and molecular …, 2015 - Springer
Chemotherapy is one of the major categories of medical oncology and a primary tumor
treatment; however, the effectiveness of chemotherapy is restricted by drug resistance …
treatment; however, the effectiveness of chemotherapy is restricted by drug resistance …
High level of progesteron receptor membrane component 1 (PGRMC 1) in tissue of breast cancer patients is associated with worse response to anthracycline-based …
M Willibald, I Wurster, C Meisner… - Hormone and …, 2017 - thieme-connect.com
PGRMC1 is known to be highly expressed in breast cancer tissue and is associated with
chemoresistance in breast cancer cells. However, its role in breast cancer signaling is not …
chemoresistance in breast cancer cells. However, its role in breast cancer signaling is not …
Progesterone receptor membrane component 1 (PGRMC1) binds and stabilizes cytochromes P450 through a heme-independent mechanism
MR McGuire, D Mukhopadhyay, SL Myers… - Journal of Biological …, 2021 - ASBMB
Progesterone receptor membrane component 1 (PGRMC1) is a heme-binding protein
implicated in a wide range of cellular functions. We previously showed that PGRMC1 binds …
implicated in a wide range of cellular functions. We previously showed that PGRMC1 binds …
[HTML][HTML] G-protein coupled receptor family C, group 5, member A (GPRC5A) expression is decreased in the adjacent field and normal bronchial epithelia of patients …
J Fujimoto, H Kadara, MM Garcia, M Kabbout… - Journal of thoracic …, 2012 - Elsevier
Introduction: Understanding oncogenes and tumor suppressor genes expression patterns is
essential for characterizing lung cancer pathogenesis. We have previously demonstrated …
essential for characterizing lung cancer pathogenesis. We have previously demonstrated …
Signaling, physiological functions and clinical relevance of the G protein-coupled estrogen receptor GPER
ER Prossnitz, M Barton - Prostaglandins & other lipid mediators, 2009 - Elsevier
GPR30, now named GPER1 (G protein-coupled estrogen receptor1) or GPER here, was first
identified as an orphan 7-transmembrane G protein-coupled receptor by multiple …
identified as an orphan 7-transmembrane G protein-coupled receptor by multiple …
Association of circulating Progesterone Receptor Membrane Component-1 (PGRMC1) with PGRMC1 expression in breast tumour tissue and with clinical breast …
G Cai, X Yang, X Ruan, J Wang, Y Fang, Y Wei… - Maturitas, 2020 - Elsevier
Objectives Progesterone receptor membrane component-1 (PGRMC1) in breast cancer
tissue has been suggested to predict a worse prognosis. The aim of this study was to assess …
tissue has been suggested to predict a worse prognosis. The aim of this study was to assess …
The role of progesterone receptor membrane component (PGRMC) in the endometrium
DMV Hernández, ER Vázquez-Martínez… - Steroids, 2022 - Elsevier
PGRMC is a non-classical receptor that mediates the non-genomic responses to
progesterone and is distributed in different subcellular compartments. PGRMC belongs to …
progesterone and is distributed in different subcellular compartments. PGRMC belongs to …
Enhancement of cell surface expression and receptor functions of membrane progestin receptor α (mPRα) by progesterone receptor membrane component 1 …
P Thomas, Y Pang, J Dong - Endocrinology, 2014 - academic.oup.com
A variety of functions have been proposed for progesterone receptor membrane component
1 (PGRMC1), including acting as a component of a membrane progestin receptor and as an …
1 (PGRMC1), including acting as a component of a membrane progestin receptor and as an …