Progesterone inhibits apoptosis in part by PGRMC1-regulated gene expression
JJ Peluso, X Liu, A Gawkowska, V Lodde… - Molecular and cellular …, 2010 - Elsevier
Progesterone receptor membrane component-1 (PGRMC1) is present in both the cytoplasm
and nucleus of spontaneously immortalized granulosa cells (SIGCs). PGRMC1 is detected …
and nucleus of spontaneously immortalized granulosa cells (SIGCs). PGRMC1 is detected …
Association of circulating Progesterone Receptor Membrane Component-1 (PGRMC1) with breast tumor characteristics and comparison with known tumor markers
X Ruan, G Cai, Y Wei, M Gu, Y Zhang, Y Zhao… - Menopause, 2020 - journals.lww.com
Objectives: Progesterone receptor membrane component-1 (PGRMC1) expressed in breast
cancer tissue has been suggested to predict a worse prognosis. The aim of this study was to …
cancer tissue has been suggested to predict a worse prognosis. The aim of this study was to …
Regulation of ovarian cancer cell viability and sensitivity to cisplatin by progesterone receptor membrane component-1
JJ Peluso, X Liu, MM Saunders… - The Journal of …, 2008 - academic.oup.com
Abstract Context: Progesterone (P4) influences ovarian cancer cells by an unknown
mechanism. Objective: The objective was to determine whether P4 acts through …
mechanism. Objective: The objective was to determine whether P4 acts through …
Progesterone receptor (PR) polyproline domain (PPD) mediates inhibition of epidermal growth factor receptor (EGFR) signaling in non-small cell lung cancer cells
S Kawprasertsri, RJ Pietras, DC Marquez-Garban… - Cancer letters, 2016 - Elsevier
Recent evidence has suggested a possible role for progesterone receptor (PR) in the
progression of non-small cell lung cancer (NSCLC). However, little is known concerning …
progression of non-small cell lung cancer (NSCLC). However, little is known concerning …
Progesterone receptor membrane component-1 (PGRMC1) is the mediator of progesterone's antiapoptotic action in spontaneously immortalized granulosa cells as …
JJ Peluso, J Romak, X Liu - Endocrinology, 2008 - academic.oup.com
Progesterone (P4) receptor membrane component-1 (PGRMC1) and its binding partner,
plasminogen activator inhibitor 1 RNA binding protein (PAIRBP1) are thought to form a …
plasminogen activator inhibitor 1 RNA binding protein (PAIRBP1) are thought to form a …
In vitro inhibition of SKOV-3 cell migration as a distinctive feature of progesterone receptor membrane component type 2 versus type 1
C Albrecht, V Huck, M Wehling, A Wendler - Steroids, 2012 - Elsevier
Progesterone receptor membrane component type 2 (PGRMC2) is strongly homologous to
PGRMC1 which is highly expressed in ovarian cancer and other cancer cells and was …
PGRMC1 which is highly expressed in ovarian cancer and other cancer cells and was …
Clinical importance of PGRMC1 in hormone responsive breast cancer
X Ruan, AO Mueck - Breast Care, 2023 - karger.com
Background: For the development of PGRMC1, a multifunctional receptor belonging to
membrane-associated progesterone receptor proteins (MAPR) family, as possible predictive …
membrane-associated progesterone receptor proteins (MAPR) family, as possible predictive …
[HTML][HTML] Cell-penetrating peptides containing the progesterone receptor polyproline domain inhibits EGF signaling and cell proliferation in lung cancer cells
Non-small cell lung cancer (NSCLC) accounts for the majority (80–85%) of all lung cancers.
All current available treatments have limited efficacy. The epidermal growth factor receptor …
All current available treatments have limited efficacy. The epidermal growth factor receptor …
G protein-coupled estrogen receptor (GPER) mediates NSCLC progression induced by 17β-estradiol (E2) and selective agonist G1
C Liu, Y Liao, S Fan, H Tang, Z Jiang, B Zhou, J Xiong… - Medical oncology, 2015 - Springer
Estrogen classically drives lung cancer development via estrogen receptor β (ERβ).
However, fulvestrant, an anti-estrogen-based endocrine therapeutic treatment, shows limited …
However, fulvestrant, an anti-estrogen-based endocrine therapeutic treatment, shows limited …
Perspectives on membrane-associated progesterone receptors as prospective therapeutic targets
S Hasegawa, M Kasubuchi, K Terasawa… - Current drug …, 2016 - ingentaconnect.com
Progesterone receptor membrane components 1 and 2, neudesin, and neuferricin belong to
the membraneassociated progesterone receptor (MAPR) family. Recently, sex steroid …
the membraneassociated progesterone receptor (MAPR) family. Recently, sex steroid …