Replication of a pathogenic non-coding RNA increases DNA methylation in plants associated with a bromodomain-containing viroid-binding protein

DQ Lv, SW Liu, JH Zhao, BJ Zhou, SP Wang… - Scientific Reports, 2016 - nature.com
Viroids are plant-pathogenic molecules made up of single-stranded circular non-coding
RNAs. How replicating viroids interfere with host silencing remains largely unknown. In this …

Replicating Potato spindle tuber viroid mediates de novo methylation of an intronic viroid sequence but no cleavage of the corresponding pre-mRNA

A Dalakouras, E Dadami, A Bassler, M Zwiebel… - RNA biology, 2015 - Taylor & Francis
In plants, Potato spindle tuber viroid (PSTVd) replication triggers post-transcriptional gene
silencing (PTGS) and RNA-directed DNA methylation (RdDM) of homologous RNA and DNA …

Viroid‐induced RNA silencing of GFP‐viroid fusion transgenes does not induce extensive spreading of methylation or transitive silencing

U Vogt, T Pélissier, A Pütz, F Razvi, R Fischer… - The Plant …, 2004 - Wiley Online Library
Viroid infection is associated with the production of short interfering RNAs (siRNAs), a
hallmark of post‐transcriptional gene silencing (PTGS). However, viroid RNAs …

Viroids and gene silencing

V Conejero - Viroids. CSIRO Publishing, Collingwood, Australia, 2003 - books.google.com
Viroids have the lowest biological complexity of known pathogens (naked RNAs, with a
molecular mass of about 105 Da). Their informational content is about one-tenth that of a …

PSTVd infection in Nicotiana benthamiana plants has a minor yet detectable effect on CG methylation

M Tselika, N Belmezos, P Kallemi, C Andronis… - Frontiers in Plant …, 2023 - frontiersin.org
Viroids are small circular RNAs infecting a wide range of plants. They do not code for any
protein or peptide and therefore rely on their structure for their biological cycle. Observed …

RNA silencing and viroids

M Barba, A Hadidi - Journal of Plant Pathology, 2009 - JSTOR
Viroids are autonomously replicating, small singlestranded circular RNA molecules that do
not code for proteins and may cause disease in infected, susceptible plants. Viroids have the …

Viroid infection and host epigenetic alterations

J Marquez-Molins, G Martinez, V Pallás… - Fundamentals of Viroid …, 2024 - Elsevier
It is well established that viroids promote significant alterations at diverse host regulatory
levels. In the last years diverse studies have revealed the existence of a close interplay …

[HTML][HTML] Plant epigenome alterations: an emergent player in viroid-host interactions

G Gómez, J Marquez-Molins, G Martinez, V Pallas - Virus Research, 2022 - Elsevier
It is well known that viroids promote significant alterations at diverse host regulatory levels.
However the mechanisms by which these tiny RNAs subvert endogenous regulatory …

Potato spindle tuber viroid modulates its replication through a direct interaction with a splicing regulator

J Jiang, HN Smith, D Ren… - Journal of …, 2018 - Am Soc Microbiol
Viroids are circular noncoding RNAs (ncRNAs) that infect plants. Despite differences in the
genetic makeup and biogenesis, viroids and various long ncRNAs all rely on RNA structure …

Alterations in host DNA methylation in response to constitutive expression of Hop stunt viroid RNA in Nicotiana benthamiana plants

M Castellano, G Martinez, V Pallás, G Gómez - Plant pathology, 2015 - Wiley Online Library
Increasing evidence points to the epigenetic regulation of transcriptional activity as a
general mechanism controlling host response to pathogen infection. Recent results revealed …