Cisplatin, a highly effective chemotherapeutic drug for various human cancers, induces
irreversible sensorineural hearing loss as a side effect. Currently there are no highly …

Cisplatin-induced ototoxicity in humans is more predominant in the cochlea than in the
vestibule. Neither definite nor substantial vestibular dysfunction after cisplatin treatment has …

Cisplatin is one of the most widely used chemotherapeutic drugs across the world. However,
the serious ototoxic effects, leading to permanent hair cell death and hearing loss …

Cisplatin is a known ototoxic chemotherapy drug, causing irreversible hearing loss.
Evidence has shown that cisplatin causes inner ear damage as a result of adduct formation …

Cisplatin chemotherapy often causes permanent hearing loss, which leads to a multifaceted
decrease in quality of life. Identification of early cisplatin-induced cochlear damage would …

Cisplatin is a platinum-based drug, which remains among the most efficacious anticancer
treatment options. Unfortunately, use of cisplatin is hindered by dose-limiting toxicities …

Cisplatin belongs to platinum-based drugs and is widely used in cancer chemotherapy.
Ototoxicity is one of the major dose limiting side-effects of cisplatin. For toxicity to occur …

Ototoxicity is a dose-limiting side effect of chemotherapeutic treatment with cisplatin. In a
series of experiments on neonatal rat cochlear organotypic cultures, the extent of damage …

Cisplatin is a highly effective antineoplastic agent used to treat solid tumors. Unfortunately,
the administration of this drug leads to significant side effects, including ototoxicity …

Ototoxicity refers to the inner ear dysfunction caused by a drug or a chemical agent which
manifests as hearing loss or balance impairment, or both. Currently, antibiotics, diuretics …