Current approaches to advanced-stage non–small-cell lung cancer: first-line therapy in patients with a good functional status

TE Stinchcombe, CB Lee, MA Socinski - Clinical lung cancer, 2006 - Elsevier
Lung cancer is the leading cause of cancer-related death among men and women in the
United States. Approximately 80-85% of lung cancer cases are non–small-cell lung cancer …

New drugs in advanced non-small-cell lung cancer: searching for the correct clinical development

M Di Maio, A Morabito, MC Piccirillo… - Expert Opinion on …, 2010 - Taylor & Francis
Importance of the field: Non-small-cell lung cancer (NSCLC) is one of the most active fields
of research in oncology, with many drugs under clinical development. Most of these drugs …

Advances in the treatment of non-small cell lung cancer

L Horn - Journal of the National Comprehensive Cancer …, 2014 - jnccn.org
Clinical trial data continue to emerge on treatments in advanced non-small cell lung cancer
(NSCLC), supporting the strategy that histology and molecular driver mutations should guide …

Advances in chemotherapy in advanced non-small-cell lung cancer

P Maione, A Rossi, PC Sacco… - Expert opinion on …, 2010 - Taylor & Francis
Importance of the field: Lung cancer is the most common cancer in the world today, in terms
of both incidence and mortality. Non-small-cell lung cancer (NSCLC) accounts for about …

Second-Line Treatment for Advanced-Stage Non–Small-Cell Lung Cancer: Current and Future Options

C Ho, AM Davies, JPN Lara, DR Gandara - Clinical lung cancer, 2006 - Elsevier
Non–small-cell lung cancer is the leading cause of cancer-related death in men and women.
Because of its frequent presentation as advanced disease, most non–small-cell lung …

Implications of key trials in advanced nonsmall cell lung cancer

PD Bonomi - … International Journal of the American Cancer …, 2010 - Wiley Online Library
Many different targeted therapies with varying mechanisms of action have been added to
standard first‐line chemotherapy doublets in an effort to improve survival of patients with …

Treatment paradigms in advanced non-small-cell lung cancer.

CE McCoach, K Kelly - Clinical Advances in Hematology and …, 2013 - escholarship.org
Lung cancer is the most common cause of cancer-related death worldwide, owing to its
metastatic spread at the time of diagnosis. As a result, chemotherapy is the standard of care …

Targeted therapies for advanced non-small-cell lung cancer: current status and future implications

A Custodio, M Méndez, M Provencio - Cancer treatment reviews, 2012 - Elsevier
Lung cancer remains the leading cause of malignancy-related mortality worldwide, with over
one million cases diagnosed yearly. Non-small-cell lung cancer (NSCLC) accounts for> …

Management of patients with advanced non-small cell lung cancer: current and emerging options

LR Triano, H Deshpande, SN Gettinger - Drugs, 2010 - Springer
Systemic therapy for advanced non-small cell lung cancer (NSCLC) has evolved over the
last two decades, with modest improvements in quality of life and overall survival. A plateau …

Treatment of non-small-cell lung cancer: state of the art and development of new biologic agents

C Gridelli, A Rossi, P Maione - Oncogene, 2003 - nature.com
Conventional treatment of non-small-cell lung cancer (NSCLC) has apparently reached a
plateau of effectiveness in improving the survival of NSCLC patients. Although neoadjuvant …