Introduction: Recent research has unravelled an increasing list of cardiac conditions and risk
factors that may be responsible for the abnormal underlying atrial substrate that predisposes …

Atrial myopathy is a condition that consists of electrical, structural, contractile, and autonomic
remodeling of the atria and is the substrate for development of atrial fibrillation, the most …

Atrial fibrillation (AF) is an important cause of stroke and risk factor for heart failure and
death. Current pharmacologic treatments for AF have limited efficacy, and treatments that …

Atrial fibrillation (AF) is an arrhythmia that can occur as the result of numerous different
pathophysiological processes in the atria. Some aspects of the morphological and …

Atrial fibrillation (AF) is the most common arrhythmia in clinical practice. The prevalence of
AF increases dramatically with age and is seen in as high as 9% of individuals by the age of …

Thyroid hormone plays an important role in cardiac electrophysiology and Ca2+ handling
through both genomic and nongenomic mechanisms of action, while both actions can …

Background Heart failure (HF) is associated with increased atrial fibrillation (AF) risk.
Accumulating evidence suggests the presence of myocardial tissue hypothyroidism in HF …

Atrial fibrillation (AF) is the most commonly encountered arrhythmia in clinical practice.
Despite advances in our understanding of the pathophysiology of this complex arrhythmia …

Accumulating evidence links calcium-overload and oxidative stress to atrial remodeling
during atrial fibrillation (AF). Furthermore, atrial remodeling appears to increase atrial …

Atrial fibrillation is the most common rhythm disturbance encountered in clinical practice.
Although often considered as solely arrhythmic in nature, current evidence has established …