[HTML][HTML] The complex relation between atrial cardiomyopathy and thrombogenesis

E D'Alessandro, J Winters, FA van Nieuwenhoven… - Cells, 2022 - mdpi.com
Heart disease, as well as systemic metabolic alterations, can leave a 'fingerprint'of structural
and functional changes in the atrial myocardium, leading to the onset of atrial …

Losartan affects the substrate for atrial fibrillation maintenance in a rabbit model

Y Zhao, T Gu, G Zhang, H Liu, C Wang - Cardiovascular Pathology, 2013 - Elsevier
Background Atrial fibrosis causes abnormal conduction through the atria, creating a
substrate for atrial fibrillation (AF). In a rabbit model, rapid atrial pacing produces significant …

Alterations in atrial ion channels and tissue structure promote atrial fibrillation in hypothyroid rats

J Li, Z Liu, H Zhao, F Yun, Z Liang, D Wang, X Zhao… - Endocrine, 2019 - Springer
Purpose It is well known that hyperthyroidism is associated with atrial fibrillation (AF);
however, the relationship between hypothyroidism and AF remains controversial. Methods …

[HTML][HTML] Profibrotic, electrical, and calcium-handling remodeling of the atria in heart failure patients with and without atrial fibrillation

CE Molina, IH Abu-Taha, Q Wang… - Frontiers in …, 2018 - frontiersin.org
Atrial fibrillation (AF) and heart failure (HF) are common cardiovascular diseases that often
co-exist. Animal models have suggested complex AF-promoting atrial structural, electrical …

Signal transduction systems and atrial fibrillation

A Goette, U Lendeckel, HU Klein - Cardiovascular research, 2002 - academic.oup.com
Cell communication, an essential component of integrated physiological function in
multicellular organisms, is mediated largely through informational molecules, such as …

Comprehensive evaluation of electrophysiological and 3D structural features of human atrial myocardium with insights on atrial fibrillation maintenance mechanisms

AV Mikhailov, A Kalyanasundaram, N Li… - Journal of molecular and …, 2021 - Elsevier
Atrial fibrillation (AF) occurrence and maintenance is associated with progressive
remodeling of electrophysiological (repolarization and conduction) and 3D structural …

Molecular and cellular mechanisms of atrial fibrosis in atrial fibrillation

S Nattel - JACC: Clinical Electrophysiology, 2017 - jacc.org
Atrial fibrillation (AF) is the most common arrhythmia in clinical practice. Atrial fibrosis has
emerged as an important pathophysiological contributor and has been linked to AF …

Electrical and structural remodeling: role in the genesis and maintenance of atrial fibrillation

BA Schoonderwoerd, IC Van Gelder… - Progress in …, 2005 - Elsevier
Atrial fibrillation (AF) and congestive heart failure (CHF) are 2 frequently encountered
conditions in clinical practice. Both lead to changes in atrial function and structure, an array …

Redox control of cardiac remodeling in atrial fibrillation

C Wolke, A Bukowska, A Goette, U Lendeckel - Biochimica et Biophysica …, 2015 - Elsevier
Background Atrial fibrillation (AF) is the most common arrhythmia in clinical practice and is a
potential cause of thromboembolic events. AF induces significant changes in the …

Thyroid hormone and cardioprotection

AM Gerdes, K Ojamaa - Comprehensive Physiology, 2011 - Wiley Online Library
The heart is a major target of thyroid hormones, with maintenance of euthyroid hormone
balance critical for proper function. In particular, chronic low thyroid function can eventually …