Obesity is characterized as a chronic state of low‐grade inflammation with progressive
immune cell infiltration into adipose tissues. Adipose tissue macrophages play critical roles …

In obesity, chronic low-grade inflammation is thought to mediate the effects of increased
adipose tissue mass on metabolic comorbidity. Of the different cell types that contribute to …

Macrophage infiltration into adipose tissue is a key pathological factor inducing adipose
tissue dysfunction and contributing to obesity-induced inflammation and metabolic …

Obesity is characterized by the chronic low-grade activation of the innate immune system. In
this respect, macrophage-elicited metabolic inflammation and adipocyte-macrophage …

Adipose tissue is a complex organ that comprises a wide range of cell types with diverse
energy storage, metabolic regulation, and neuroendocrine and immune functions. Because …

This review summarizes the role of macrophages in adipose tissue remodeling, particularly
focusing on the paracrine loop between adipocytes and macrophages. The adipose tissue …

Inflammation originating from the adipose tissue is considered to be one of the main driving
forces for the development of insulin resistance and type 2 diabetes in obese individuals …

It has long been known that adipose tissue in obesity is in a heightened state of
inflammation. Recently, our understanding of this has been transformed by the knowledge …

Obesity is a condition likely associated with several dysmetabolic conditions or worsening of
cardiovascular and other chronic disturbances. A key role in this mechanism seem to be …

The obesity epidemic has led researchers and clinicians to reconsider the etiology of this
disease and precisely decipher its molecular mechanisms. The excessive accumulation of …