The blood–brain barrier (BBB) is a natural obstacle for drug delivery into the human brain,
hindering treatment of central nervous system (CNS) disorders such as acute ischemic …

The blood-brain barrier (BBB), which protects the central nervous system (CNS) from
unnecessary substances, is a challenging obstacle in the treatment of CNS disease. Many …

Neurological disorders are an important global public health problem, but pharmaceutical
treatments are limited due to drug access to the central nervous system being restricted by …

Treatment of neurodegenerative diseases has become one of the most challenging topics of
the last decades due to their prevalence and increasing societal cost. The crucial point of the …

Amphiphilic block co-polymer nanoparticles are interesting candidates for drug delivery as a
result of their unique properties such as the size, modularity, biocompatibility and drug …

Nanomedicine is certainly one of the scientific and technological challenges of the coming
years. In particular, biodegradable nanoparticles formulated from poly (D, L-lactide-co …

Polymers were first introduced three decades ago as bioresorbable surgical devices. Since
then, polymer-based nanoparticles have been extensively studied in a variety of fields …

The blood–brain barrier (BBB) acts as a barrier to prevent the central nervous system (CNS)
from damage by substances that originate from the blood circulation. The BBB limits drug …

In this study, we investigated surface-modified nanoparticles (NP) formulated using a
biodegradable polymer, poly (d, l-lactide-co-glycolide)(PLGA), for targeting central nervous …

Poly (lactic-co-glycolic acid)(PLGA) is one of the most successfully developed
biodegradable polymers. Among the different polymers developed to formulate polymeric …