Gene expression changes linked to antimicrobial resistance, oxidative stress, iron depletion and retained motility are observed when Burkholderia cenocepaciagrows …

P Drevinek, MTG Holden, Z Ge, AM Jones… - BMC infectious …, 2008 - Springer
Abstract Background Bacteria from the Burkholderia cepacia complex (Bcc) are the only
group of cystic fibrosis (CF) respiratory pathogens that may cause death by an invasive …

Patterns of Epithelial Cell Invasion by Different Species of the Burkholderia cepacia Complex in Well-Differentiated Human Airway Epithelia

U Schwab, M Leigh, C Ribeiro, J Yankaskas… - Infection and …, 2002 - Am Soc Microbiol
Burkholderia cepacia has emerged as a serious respiratory pathogen in cystic fibrosis (CF)
patients. The clinical course of B. cepacia infections is variable, but∼ 20% of patients …

Rapid detection of Burkholderia cepacia complex carrying the 16S rRNA gene in clinical specimens by recombinase-aided amplification

H Fu, L Gan, Z Tian, J Han, B Du, G Xue… - Frontiers in Cellular …, 2022 - frontiersin.org
The Burkholderia cepacia complex (BCC) is a group of opportunistic pathogens, including
Burkholderia cepacia, Burkholderia multivorans, Burkholderia vietnamiensis and …

Burkholderia cepacia Complex Regulation of Virulence Gene Expression: A Review

SA Sousa, JR Feliciano, T Pita, SI Guerreiro, JH Leitão - Genes, 2017 - mdpi.com
Burkholderia cepacia complex (Bcc) bacteria emerged as opportunistic pathogens in cystic
fibrosis and immunocompromised patients. Their eradication is very difficult due to the high …

Virulence traits associated with Burkholderia cenocepacia ST856 epidemic strain isolated from cystic fibrosis patients

M Malešević, Z Vasiljević, A Sovtić, B Filipić… - … Resistance & Infection …, 2017 - Springer
Background Burkholderia cenocepacia is considered one of the most problematic cystic
fibrosis (CF) pathogens. Colonization prevalence in the Serbian CF population is high and …

Mechanisms of Disease: Host-Pathogen Interactions between Burkholderia Species and Lung Epithelial Cells

J David, RE Bell, GC Clark - Frontiers in cellular and infection …, 2015 - frontiersin.org
Members of the Burkholderia species can cause a range of severe, often fatal, respiratory
diseases. A variety of in vitro models of infection have been developed in an attempt to …

[HTML][HTML] Transcriptome analysis of Burkholderia pseudomallei SCV reveals an association with virulence, stress resistance and intracellular persistence

AR Al-Maleki, KM Vellasamy, V Mariappan… - Genomics, 2020 - Elsevier
Differences in expression of potential virulence and survival genes were associated with B.
pseudomallei colony morphology variants. Microarray was used to investigate B …

Burkholderia cepacia Complex: Emerging Multihost Pathogens Equipped with a Wide Range of Virulence Factors and Determinants

SA Sousa, CG Ramos, JH Leitao - International journal of …, 2011 - Wiley Online Library
The Burkholderia cepacia complex (Bcc) comprises at least 17 closely‐related species of
the β‐proteobacteria subdivision, widely distributed in natural and man‐made inhabitats …

Novel pan-genomic analysis approach in target selection for multiplex PCR identification and detection of Burkholderia pseudomallei, Burkholderia thailandensis, and …

CC Ho, CCY Lau, P Martelli, SY Chan… - Journal of clinical …, 2011 - Am Soc Microbiol
Burkholderia pseudomallei, Burkholderia thailandensis, and the Burkholderia cepacia
complex differ greatly in pathogenicity and epidemiology. Yet, they are occasionally …

Thinking Outside the Bug: Targeting Outer Membrane Proteins for Burkholderia Vaccines

ME Grund, J Choi Soo, CK Cote, R Berisio, S Lukomski - Cells, 2021 - mdpi.com
Increasing antimicrobial resistance due to misuse and overuse of antimicrobials, as well as
a lack of new and innovative antibiotics in development has become an alarming global …