The purpose of this study was to determine the role of colonial morphology of Burkholderia
cepacia complex (BCC) organisms in pathogenicity in a mouse model of pulmonary …

Background Burkholderia cenocepacia is a human opportunistic pathogen causing
devastating symptoms in patients suffering from immunodeficiency and cystic fibrosis. Out of …

Global health therapeutics is a rapidly emerging facet of postgenomics medicine. In this
connection, Brucella melitensis is an intracellular bacterium that causes the zoonotic …

ABSTRACT PCR assays targeting rRNA genes were developed to identify species
(genomovars) within the Burkholderia cepacia complex. Each assay was tested with 177 …

The Burkholderia cepacia complex presently comprises nine genomovars: B. cepacia
(genomovar I), B. multivorans (genomovar II), B. cepacia genomovar III, B. stabilis …

Burkholderia mallei, the aetiological agent of glanders disease, is a Gram-negative
facultative intracellular bacterium. Despite numerous studies, the detailed mechanism of its …

Members of the Burkholderia cepacia complex are important bacterial pathogens in cystic
fibrosis (CF) patients. The B. cepacia complex currently consists of nine genetic subgroups …

Burkholderia pathogenicity relies on protein virulence factors to control and promote
bacterial internalization, survival, and replication within eukaryotic host cells. We recently …

Burkholderia pseudomallei, the etiologic agent of melioidosis, is an opportunistic pathogen
that harbors a wide array of secretion systems, including a type II secretion system (T2SS) …

Background Burkholderia pseudomallei is a facultative intracellular pathogen of phagocytic
and non-phagocytic cells. How the bacterium interacts with host macrophage cells is still not …