Overcoming barriers to clinical trial enrollment.

RD Nipp, K Hong, ED Paskett - American Society of Clinical …, 2019 - europepmc.org
Clinical trials are imperative for testing novel cancer therapies, advancing the science of
cancer care, and determining the best treatment strategies to enhance outcomes for patients …

[HTML][HTML] Role of clinical trial participation in cancer research: barriers, evidence, and strategies

JM Unger, E Cook, E Tai, A Bleyer - American Society of Clinical …, 2016 - ncbi.nlm.nih.gov
Fewer than 1 in 20 adult cancer patients enroll in cancer clinical trials. But although barriers
to trial participation have been the subject of frequent study, the rate of trial participation has …

Addressing financial barriers to patient participation in clinical trials: ASCO policy statement

KM Winkfield, JK Phillips, S Joffe… - Journal of Clinical …, 2018 - ascopubs.org
Research conducted through clinical trials is essential for evaluating new treatment
modalities, establishing new standards of cancer care, and ultimately improving and …

Factors influencing enrollment in clinical trials for cancer treatment.

CN Klabunde, BC Springer, B Butler… - Southern Medical …, 1999 - europepmc.org
BACKGROUND: Recruitment of cancer patients to clinical trials is an ongoing challenge. In
this study, we assess factors that may influence enrollment in clinical trials for cancer …

Systematic review and meta-analysis of the magnitude of structural, clinical, and physician and patient barriers to cancer clinical trial participation

JM Unger, R Vaidya, DL Hershman… - JNCI: Journal of the …, 2019 - academic.oup.com
Background Barriers to cancer clinical trial participation have been the subject of frequent
study, but the rate of trial participation has not changed substantially over time. Studies often …

Modernizing eligibility criteria for molecularly driven trials

ES Kim, D Bernstein, SG Hilsenbeck… - Journal of Clinical …, 2015 - ascopubs.org
As more clinical trials of molecularly targeted agents evolve, the number of eligibility criteria
seems to be increasing. The importance and utility of eligibility criteria must be considered in …

Financial toxicity and equitable access to clinical trials.

F Chino, SY Zafar - … Society of Clinical Oncology Educational book …, 2019 - europepmc.org
Financial barriers to clinical trial enrollment are an area of active investigation. Financial
toxicity as a concept describes how high costs and financial burden can lead to …

Strategies to advance equity in cancer clinical trials

CE Guerra, ME Fleury, LP Byatt, T Lian… - American Society of …, 2022 - ascopubs.org
Cancer clinical trials are critical for testing new treatments, yet less than 5% of patients with
cancer enroll in these trials. Minority groups, elderly individuals, and rural populations are …

Barriers to clinical trial participation as perceived by oncologists and patients

NJ Meropol, JS Buzaglo, J Millard, N Damjanov… - Journal of the National …, 2007 - jnccn.org
Although clinical trial research is required for the development of improved treatment
strategies, very few cancer patients participate in these studies. The purpose of this study …

Reducing patient eligibility criteria in cancer clinical trials.

SL George - Journal of Clinical Oncology, 1996 - ascopubs.org
PURPOSE To discuss patient eligibility criteria in phase III cancer clinical trials in the larger
setting of the complexity of these trials, to review the various reasons for imposing restrictive …