Apolipoprotein B is a large, amphipathic protein that plays a central role in lipoprotein
metabolism. Because its overproduction and deficiency leads to metabolic and pathologic …

Two forms of apolipoprotein (apo) B are found in mammals. The shorter form is translated
from an edited mRNA in which a specific cytidine base is deaminated to a uridine, creating a …

Apolipoprotein (apo) B mRNA editing consists of a C→ U conversion of the first base of the
codon CAA encoding glutamine 2153 in apoB mRNA to UAA, a stop codon. The cDNA for …

Apolipoprotein (apo) B occurs in two forms, apoB100 (512 kDa) and apoB48 (240 kDa); both
are derived from the same gene. A novel mechanism involving editing of the apoB mRNA …

The objective of this study was to establish conditions whereby apoB secreted from HepG2
cells could be regulated over a wide range, and to determine whether changes of output …

Objectives: Hepatic overproduction of apolipoprotein B (apoB)-containing lipoproteins
appears to be a common cause of hyperlipoproteinemia in humans. Patients with …

Apolipoprotein (apo) B mRNA undergoes a novel tissue-specific editing reaction, which
replaces a genomically templated cytidine with uridine. This substitution converts codon …

Apolipoprotein B (apoB) messenger RNA (mRNA) undergoes posttranscriptional (C to U)
editing, producing tissue-specific forms of apoB from the unedited (apoB100) and edited …

To explore the process of lipoprotein assembly, plasmids encoding truncated forms of
apolipoprotein B (apoB) were transfected into Chinese hamster ovary (CHO) …

Apolipoprotein B (ApoB) is a major constituent of the plasma lipoproteins. In adult mammals
it is synthesized in two different tissues, liver and intestine. We have examined the promoter …