Expression and occupancy of BAFF‐R on B cells in systemic lupus erythematosus

RH Carter, H Zhao, X Liu, M Pelletier… - Arthritis & …, 2005 - Wiley Online Library
Objective To determine whether receptors for B lymphocyte stimulator (BLyS) are altered on
B cells of patients with systemic lupus erythematosus (SLE). Methods Total available …

Increase of B cell-activating factor of the TNF family (BAFF) after rituximab treatment: insights into a new regulating system of BAFF production

F Lavie, C Miceli-Richard, M Ittah, J Sellam… - Annals of the …, 2007 - ard.bmj.com
Background: The cytokine B cell-activating factor of the TNF family (BAFF) is involved in the
pathogenesis of autoimmune diseases. Objective: To access changes in serum protein and …

[HTML][HTML] Intrarenal production of B-cell survival factors in human lupus nephritis

MA Neusser, MT Lindenmeyer, I Edenhofer, S Gaiser… - Modern Pathology, 2011 - Elsevier
The B-cell survival factors APRIL and BLyS are important for B-cell maturation and activation
and contribute to human autoimmune diseases. Interference with B-cell function by targeting …

Differential effects on BAFF and APRIL levels in rituximab-treated patients with systemic lupus erythematosus and rheumatoid arthritis

T Vallerskog, M Heimbürger, I Gunnarsson… - Arthritis research & …, 2006 - Springer
The objective of this study was to investigate the interaction between levels of BAFF (B-cell
activation factor of the tumour necrosis factor [TNF] family) and APRIL (a proliferation …

Elevated serum BAFF levels are associated with rising anti–double‐stranded DNA antibody levels and disease flare following B cell depletion therapy in systemic …

LM Carter, DA Isenberg… - Arthritis & Rheumatism, 2013 - Wiley Online Library
Objective To determine whether serum BAFF levels correlate with relapse or remission in
patients with systemic lupus erythematosus (SLE) following B cell depletion therapy (BCDT) …

B cell alterations during BAFF inhibition with belimumab in SLE

D Ramsköld, I Parodis, T Lakshmikanth, N Sippl… - …, 2019 - thelancet.com
Background Systemic lupus erythematosus (SLE) is a systemic autoimmune disease, which
exhibits multiple B cell abnormalities including expanded populations of memory B cells and …

BAFF: a fundamental survival factor for B cells

F Mackay, JL Browning - Nature Reviews Immunology, 2002 - nature.com
B-cell-activating factor of the tumour-necrosis-factor family (BAFF) enhances B-cell survival—
a function that is indispensable for B-cell maturation—and has a role in enhancing immune …

Paucity of clinical disease despite serological autoimmunity and kidney pathology in lupus-prone New Zealand mixed 2328 mice deficient in BAFF

CO Jacob, L Pricop, C Putterman, MN Koss… - The Journal of …, 2006 - journals.aai.org
Constitutive overexpression of B cell-activating factor belonging to the TNF family (BAFF)
promotes development of systemic lupus erythematosus (SLE), and treatment of SLE mice …

The function of BAFF on T helper cells in autoimmunity

M Chen, X Lin, Y Liu, Q Li, Y Deng, Z Liu… - Cytokine & growth factor …, 2014 - Elsevier
B cell-activating factor belonging to the TNF family (BAFF) exerts its pathogenic role in
supporting the survival and proliferation of B cells, regulating class switch recombination as …

B-lymphocyte activating factor in systemic lupus erythematosus and rheumatoid arthritis in relation to autoantibody levels, disease measures and time

A Becker-Merok, C Nikolaisen, HC Nossent - Lupus, 2006 - journals.sagepub.com
Overexpression of B-lymphocyte activating factor (BAFF) results in arthritis,
glomerulonephritis and autoantibody formation in mice, but its role in human autoimmune …