The B‐cell activity factor (BAFF) acts as a positive regulator of B‐cell function. To gain further
insight into the understanding of B‐cell hyperactivity in autoimmune diseases, the serum …

Patients with systemic lupus erythematosus (SLE) and primary Sjögren's syndrome (pSS)
are typically characterized by the presence of autoantibodies and an IFN-signature. The …

Objective To determine the association of plasma B lymphocyte stimulator (BLyS) levels,
immunosuppressive therapy, and other clinical parameters with disease activity in systemic …

Objective To understand the effects of long‐term BLyS inhibition in human systemic lupus
erythematosus (SLE). Methods Seventeen patients with SLE who were enrolled in a clinical …

B cells may have a negative regulatory role, mainly mediated by interleukin 10 (IL-10). We
recently showed that regulatory B-cell functions are impaired in patients with rheumatoid …

Background: Increased levels of B lymphocyte stimulator (BLyS) have been detected in
serum from patients with systemic lupus erythematosus and rheumatoid arthritis. Objective …

The pathogenic roles for B cells in autoimmunity include produce pathogenic autoantibodies
and modulate immune responses via the production of cytokines and chemokines. The B …