We evaluated the relationship between apical surface fluid (ASF) and protein secretion in
Calu-3 cells grown at an air–liquid interface. Calu-3 monolayers responded to forskolin, a …

Intracellular pH (pHi) plays an important role in regulating fluid and electrolyte secretion by
salivary gland acinar cells. The pH‐sensitive, fluorescent dye 2′, 7′‐bis (carboxyethyl)− 5 …

Because of the lack of salivary gland cell lines suitable for Ussing chamber studies, a
recently established rat parotid acinar cell line, Par-C10, was grown on permeable supports …

Submucosal glands line the cartilaginous airways and produce most of the antimicrobial
mucus that keeps the airways sterile. The glands are defective in cystic fibrosis (CF), but how …

Major advances in understanding regulated mucin secretion from airway goblet cells have
been made in the past decade in the areas of pharmacology and basic cell biology. For …

To determine the responsiveness of tracheal mucous cells to adrenergic and cholinergic
stimulation, we analyzed changes in their structure induced by neurotransmitter-like …

ATP in airway surface liquid (ASL) controls mucociliary clearance functions via the activation
of airway epithelial purinergic receptors. However, abnormally elevated ATP levels have …

The purpose of this study was to characterize basolateral anion channels in Calu-3 and
normal human bronchial epithelial cells, and their role in anion secretion. Patch clamp …

A balance sheet describing the integrated homeostasis of secretion, absorption, and surface
movement of liquids on pulmonary surfaces has remained elusive. It remains unclear …

Submucosal glands are the major mucus-secreting cells in the tracheobronchial tree, and
they appear to be affected in cystic fibrosis (CF). To study the dysregulation of pulmonary …