Abstract Purpose The enzyme Cyclooxygenases (COX-1 and COX-2) catalyze the formation
of prostaglandin, a mediator of the inflammatory pathway. Inflammation related pathological …

Objectives: Prostaglandins released by the activity of the bifunctional enzyme,
cyclooxygenase (COX) are involved in physiological functions such as protection of the …

ABSTRACT Objective: Cyclooxygenase-2 (COX-2) is inducible and is expressed only after
an inflammatory stimulus. Molecular docking is used to predict and analyze interactions …

The process of inflammation is associated with several disorders such as cardiovascular
disease, cancer and arthritis. Cyclooxygenase (COX) receptors play an important role in …

Introduction: Inflammation is implicated in many disorders, including communicable and
noncommunicable diseases. Cyclooxygenase-2 (Cox-2) is a key enzyme involved in the …

Objective: Inonotusspp., the mushroom is widely present and known for its medicinal
property. This mushroom produces several bioactive compounds with various …

Objective: Cissus quadrangularis, a perennial plant of grape family is traditionally used as
an herbal medicine for treating inflammation caused by hemorrhoids, gastric ulcer and bone …

New drug discovery is considered broadly in terms of two kinds of investigational activities
such as exploration and exploitation. Docking of small molecules in the receptor binding site …

Continuous inflammation can cause new and more severe diseases, thus effective
treatments are needed. One of the common inflammation treatments is given by reducing …

Cyclooxygenases (COX) catalyze the biosynthesis of prostaglandins from arachidonic acid,
the substrate. COX has two isoforms which are targets of non-steroidal anti-inflammatory …