[HTML][HTML] Cardiac remodeling: concepts, clinical impact, pathophysiological mechanisms and pharmacologic treatment

PS Azevedo, BF Polegato, MF Minicucci… - Arquivos brasileiros de …, 2015 - SciELO Brasil
Cardiac remodeling is defined as a group of molecular, cellular and interstitial changes that
manifest clinically as changes in size, mass, geometry and function of the heart after injury …

Ventricular remodeling after myocardial infarction: concepts and clinical implications

LAM Zornoff, SAR Paiva, DR Duarte… - Arquivos brasileiros de …, 2009 - SciELO Brasil
Background The word'remodeling'was used for the first time in association with myocardial
ischemia in 1982 by Hockman and Buckey while addressing the replacement of necrotic …

Remodeling in the ischemic heart: the stepwise progression for heart

JG Mill, I Stefanon, L Dos Santos… - Brazilian Journal of …, 2011 - SciELO Brasil
Coronary artery disease is the leading cause of death in the developed world and in
developing countries. Acute mortality from acute myocardial infarction (MI) has decreased in …

Reverse cardiac remodeling: a marker of better prognosis in heart failure

JRAR Reis Filho, JN Cardoso… - Arquivos brasileiros de …, 2015 - SciELO Brasil
In heart failure syndrome, myocardial dysfunction causes an increase in neurohormonal
activity, which is an adaptive and compensatory mechanism in response to the reduction in …

Mechanisms contributing to cardiac remodelling

QQ Wu, Y Xiao, Y Yuan, ZG Ma, HH Liao, C Liu… - Clinical …, 2017 - portlandpress.com
Cardiac remodelling is classified as physiological (in response to growth, exercise and
pregnancy) or pathological (in response to inflammation, ischaemia, ischaemia/reperfusion …

Pharmacological modulation of cardiac remodeling after myocardial infarction

W Zhao, J Zhao, J Rong - Oxidative Medicine and Cellular …, 2020 - Wiley Online Library
Cardiac remodeling describes a series of structural and functional changes in the heart after
myocardial infarction (MI). Adverse post‐MI cardiac remodeling directly jeopardizes the …

Cardiac remodeling—concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling

JN Cohn, R Ferrari, N Sharpe… - Journal of the American …, 2000 - jacc.org
Cardiac remodeling is generally accepted as a determinant of the clinical course of heart
failure (HF). Defined as genome expression resulting in molecular, cellular and interstitial …

Left ventricular remodeling after myocardial infarction: from physiopathology to treatment

SA Leancă, D Crișu, AO Petriș, I Afrăsânie, A Genes… - Life, 2022 - mdpi.com
Myocardial infarction (MI) is the leading cause of death and morbidity worldwide, with an
incidence relatively high in developed countries and rapidly growing in developing …

Implication of cardiac remodeling in heart failure: mechanisms and therapeutic strategies

H Takano, H Hasegawa, T Nagai, I Komuro - Internal Medicine, 2003 - jstage.jst.go.jp
Theconcept and clinical implication of left ventricular remodeling have been gradually
extended. Cardiac re-modeling plays important roles in the progression of car-diovascular …

Cardiac remodelling–Part 1: From cells and tissues to circulating biomarkers. A review from the Study Group on Biomarkers of the Heart Failure Association of the …

A González, AM Richards, RA de Boer… - European journal of …, 2022 - Wiley Online Library
Cardiac remodelling refers to changes in left ventricular structure and function over time,
with a progressive deterioration that may lead to heart failure (HF) development (adverse …