Doublet and triplet microtubules are essential and highly stable core structures of centrioles,
basal bodies, cilia, and flagella. In contrast to dynamic cytoplasmic microtubules, their …

The core structure of motile cilia and flagella, the axoneme, is built from a stable population
of doublet microtubules. This unique stability is brought about, at least in part, by a network …

Cilia, the hair-like protrusions that beat at high frequencies to propel a cell or move fluid
around are composed of radially bundled doublet microtubules. In this study, we present a …

Cilia are ubiquitous eukaryotic organelles responsible for cellular motility and sensory
functions. The ciliary axoneme is a microtubule-based cytoskeleton consisting of two central …

Doublet microtubules (DMTs) provide a scaffold for axoneme assembly in motile cilia. Aside
from α/β tubulins, the DMT comprises a large number of non-tubulin proteins in the luminal …

Motile eukaryotic cilia and flagella are hair‐like organelles responsible for cell motility and
mucociliary clearance. Using cryo‐electron tomography, it has been shown that the doublet …

Thanks to recent technological advances, the ciliate Tetrahymena thermophila has emerged
as an attractive model organism for studies on the assembly of microtubular organelles in a …

Radial spokes are conserved macromolecular complexes that are essential for ciliary
motility. A triplet of three radial spokes, RS1, RS2, and RS3, repeats every 96 nm along the …

Centrosomes and cilia are microtubule-based superstructures vital for cell division,
signaling, and motility. The once thought hollow lumen of their microtubule core structures …

Cilia are ubiquitous, hair-like appendages found in eukaryotic cells that carry out functions of
cell motility and sensory reception. Cilia contain an intriguing cytoskeletal structure, termed …