Successful Transplantation of Human Kidneys Deemed Untransplantable but Resuscitated by Ex Vivo Normothermic Machine Perfusion

SA Hosgood, K Saeb‐Parsy, MO Hamed… - American Journal of …, 2016 - Wiley Online Library
We report the successful transplantation of a pair of human kidneys that were declined for
transplantation due to inadequate in situ perfusion but subsequently transplanted after …

[HTML][HTML] Renal transplantation after ex vivo normothermic perfusion: the first clinical study

ML Nicholson, SA Hosgood - American Journal of Transplantation, 2013 - Elsevier
Ex vivo normothermic perfusion (EVNP) is a novel method of preservation that restores
circulation and allows an organ to regain function prior to transplantation. The aim of this …

Ex vivo normothermic perfusion for quality assessment of marginal donor kidney transplants

SA Hosgood, AD Barlow, JP Hunter… - Journal of British …, 2015 - academic.oup.com
Background A significant proportion of kidneys procured for transplantation are discarded
because of concerns about their suitability. In this study ex vivo normothermic perfusion …

[HTML][HTML] The use of ex-vivo normothermic perfusion for the resuscitation and assessment of human kidneys discarded because of inadequate in situ perfusion

SA Hosgood, AD Barlow, J Dormer… - Journal of translational …, 2015 - Springer
Background Many kidneys are rejected for transplantation due to inadequate in situ
perfusion during organ retrieval because of the risk of additional ischaemic injury and …

The First Clinical Case of Intermediate Ex Vivo Normothermic Perfusion in Renal Transplantation

SA Hosgood, ML Nicholson - American Journal of …, 2014 - Wiley Online Library
A short period of ex vivo normothermic perfusion (EVNP) immediately before transplantation
can revive the kidney and reduce the effects of cold ischemic (CI) injury. Herein, we report a …

Dissemination of a novel organ perfusion technique: ex vivo normothermic perfusion of deceased donor kidneys

P Chandak, BL Phillips, R Uwechue… - Artificial …, 2019 - Wiley Online Library
Ex vivo normothermic perfusion (EVNP) technology is a promising means of organ
preservation, assessment, and preconditioning prior to kidney transplantation, which has …

First in man renal transplantation after ex vivo normothermic perfusion

SA Hosgood, ML Nicholson - Transplantation, 2011 - journals.lww.com
Background. Normothermic perfusion is an alternative but little studied method of organ
preservation. Herein, we report the first case of ex vivo normothermic renal transplant …

[HTML][HTML] Protocol of a randomised controlled, open-label trial of ex vivo normothermic perfusion versus static cold storage in donation after circulatory death renal …

SA Hosgood, K Saeb-Parsy, C Wilson, C Callaghan… - BMJ open, 2017 - bmjopen.bmj.com
Introduction Ex vivo normothermic perfusion (EVNP) is a novel technique that reconditions
the kidney and restores renal function prior to transplantation. Phase I data from a series of …

[HTML][HTML] Normothermic ex vivo kidney perfusion for human kidney transplantation: first North American results

LI Mazilescu, P Urbanellis, SJ Kim, T Goto… - …, 2022 - journals.lww.com
Background. Normothermic ex vivo kidney perfusion (NEVKP) has shown promising results
for preservation, assessment, and reconditioning of kidney allografts in preclinical studies …

[HTML][HTML] Prolonged ex-vivo normothermic kidney perfusion: the impact of perfusate composition

MBF Pool, TL Hamelink, H van Goor… - PLoS …, 2021 - journals.plos.org
Normothermic machine perfusion (NMP) of donor kidneys provides the opportunity for
improved graft preservation and objective pre-transplant ex-vivo organ assessment …