Mapping the brain-wide network effects by optogenetic activation of the corpus callosum

Y Chen, F Sobczak, P Pais-Roldán, C Schwarz… - Cerebral …, 2020 - academic.oup.com
Optogenetically driven manipulation of circuit-specific activity enables causality studies, but
its global brain-wide effect is rarely reported. Here, we applied simultaneous functional …

Optogenetic activation of CA1 pyramidal neurons at the dorsal and ventral hippocampus evokes distinct brain-wide responses revealed by mouse fMRI

N Takata, K Yoshida, Y Komaki, M Xu, Y Sakai… - PLoS one, 2015 - journals.plos.org
The dorsal and ventral hippocampal regions (dHP and vHP) are proposed to have distinct
functions. Electrophysiological studies have revealed intra-hippocampal variances along the …

Progress with optogenetic functional MRI and its translational implications

AJ Weitz, JH Lee - Future Neurology, 2013 - Taylor & Francis
Changes in brain dynamics accompany many, if not all, neuropsychiatric and neurological
disorders. Even in health, however, the activity of global brain networks remains poorly …

Opto-fMRI analysis for exploring the neuronal connectivity of the hippocampal formation in rats

Y Abe, M Sekino, Y Terazono, H Ohsaki… - Neuroscience …, 2012 - Elsevier
In recent years, optical stimulation of neurons that bear a light-gated cation
channel,“Optogenetics”, has opened a new avenue for exploring neuronal connectivity of …

Optogenetic functional MRI

P Lin, Z Fang, J Liu, JH Lee - JoVE (Journal of Visualized Experiments), 2016 - jove.com
The investigation of the functional connectivity of precise neural circuits across the entire
intact brain can be achieved through optogenetic functional magnetic resonance imaging …

Assessing sensory versus optogenetic network activation by combining (o)fMRI with optical Ca2+ recordings

F Schmid, L Wachsmuth, M Schwalm… - Journal of Cerebral …, 2016 - journals.sagepub.com
Encoding of sensory inputs in the cortex is characterized by sparse neuronal network
activation. Optogenetic stimulation has previously been combined with fMRI (ofMRI) to probe …

Optogenetic activation of the sensorimotor cortex reveals “local inhibitory and global excitatory” inputs to the basal ganglia

M Ozaki, H Sano, S Sato, M Ogura, H Mushiake… - Cerebral …, 2017 - academic.oup.com
To understand how information from different cortical areas is integrated and processed
through the cortico-basal ganglia pathways, we used optogenetics to systematically …

Optogenetic fMRI for brain-wide circuit analysis of sensory processing

JY Lee, T You, CW Woo, SG Kim - International Journal of Molecular …, 2022 - mdpi.com
Sensory processing is a complex neurological process that receives, integrates, and
responds to information from one's own body and environment, which is closely related to …

Line scanning fMRI reveals earlier onset of optogenetically evoked BOLD response in rat somatosensory cortex as compared to sensory stimulation

F Albers, F Schmid, L Wachsmuth, C Faber - Neuroimage, 2018 - Elsevier
The combination of optogenetic control and fMRI readout in the brain is increasingly used to
assess neuronal networks and underlying signal processing. However, how exactly …

Optogenetic auditory fMRI reveals the effects of visual cortical inputs on auditory midbrain response

ATL Leong, CM Dong, PP Gao, RW Chan, A To… - Scientific reports, 2018 - nature.com
Sensory cortices contain extensive descending (corticofugal) pathways, yet their impact on
brainstem processing–particularly across sensory systems–remains poorly understood. In …