Mapping the brain-wide network effects by optogenetic activation of the corpus callosum
Optogenetically driven manipulation of circuit-specific activity enables causality studies, but
its global brain-wide effect is rarely reported. Here, we applied simultaneous functional …
its global brain-wide effect is rarely reported. Here, we applied simultaneous functional …
Optogenetic activation of CA1 pyramidal neurons at the dorsal and ventral hippocampus evokes distinct brain-wide responses revealed by mouse fMRI
N Takata, K Yoshida, Y Komaki, M Xu, Y Sakai… - PLoS one, 2015 - journals.plos.org
The dorsal and ventral hippocampal regions (dHP and vHP) are proposed to have distinct
functions. Electrophysiological studies have revealed intra-hippocampal variances along the …
functions. Electrophysiological studies have revealed intra-hippocampal variances along the …
Progress with optogenetic functional MRI and its translational implications
AJ Weitz, JH Lee - Future Neurology, 2013 - Taylor & Francis
Changes in brain dynamics accompany many, if not all, neuropsychiatric and neurological
disorders. Even in health, however, the activity of global brain networks remains poorly …
disorders. Even in health, however, the activity of global brain networks remains poorly …
Opto-fMRI analysis for exploring the neuronal connectivity of the hippocampal formation in rats
Y Abe, M Sekino, Y Terazono, H Ohsaki… - Neuroscience …, 2012 - Elsevier
In recent years, optical stimulation of neurons that bear a light-gated cation
channel,“Optogenetics”, has opened a new avenue for exploring neuronal connectivity of …
channel,“Optogenetics”, has opened a new avenue for exploring neuronal connectivity of …
Optogenetic functional MRI
The investigation of the functional connectivity of precise neural circuits across the entire
intact brain can be achieved through optogenetic functional magnetic resonance imaging …
intact brain can be achieved through optogenetic functional magnetic resonance imaging …
Assessing sensory versus optogenetic network activation by combining (o)fMRI with optical Ca2+ recordings
Encoding of sensory inputs in the cortex is characterized by sparse neuronal network
activation. Optogenetic stimulation has previously been combined with fMRI (ofMRI) to probe …
activation. Optogenetic stimulation has previously been combined with fMRI (ofMRI) to probe …
Optogenetic activation of the sensorimotor cortex reveals “local inhibitory and global excitatory” inputs to the basal ganglia
M Ozaki, H Sano, S Sato, M Ogura, H Mushiake… - Cerebral …, 2017 - academic.oup.com
To understand how information from different cortical areas is integrated and processed
through the cortico-basal ganglia pathways, we used optogenetics to systematically …
through the cortico-basal ganglia pathways, we used optogenetics to systematically …
Optogenetic fMRI for brain-wide circuit analysis of sensory processing
Sensory processing is a complex neurological process that receives, integrates, and
responds to information from one's own body and environment, which is closely related to …
responds to information from one's own body and environment, which is closely related to …
Line scanning fMRI reveals earlier onset of optogenetically evoked BOLD response in rat somatosensory cortex as compared to sensory stimulation
The combination of optogenetic control and fMRI readout in the brain is increasingly used to
assess neuronal networks and underlying signal processing. However, how exactly …
assess neuronal networks and underlying signal processing. However, how exactly …
Optogenetic auditory fMRI reveals the effects of visual cortical inputs on auditory midbrain response
Sensory cortices contain extensive descending (corticofugal) pathways, yet their impact on
brainstem processing–particularly across sensory systems–remains poorly understood. In …
brainstem processing–particularly across sensory systems–remains poorly understood. In …