Chondroitin sulphate proteoglycans (CSPGs) are one of the major families of inhibitory
extracellular matrix molecules in the central nervous system. The expression of various …

Chondroitin sulfate proteoglycans (CSPGs) are upregulated in the CNS after injury and
participate in the inhibition of axon regeneration mainly through their glycosaminoglycan …

Numerous findings support the possibility that highly sulfated proteoglycans are inhibitory
molecules which, at high concentration relative to growth-promoting signals, may regulate or …

Chondroitin sulfate proteoglycans (CSPGs), up-regulated in and around the glial scar after
mammalian spinal cord injury, have been suggested to be key inhibitory molecules for …

Chondroitinsulfate proteoglycans (CSPG) play a crucial role in the inhibition of posttraumatic
axonal regeneration in the central nervous system. Understanding of the mechanism of the …

Chondroitin sulphate proteoglycan (CSPG) inhibits axonal regeneration in the central
nervous system (CNS) and its local degradation promotes repair. We postulated that the …

Abstract Chondroitin Sulfate Proteoglycans (CSPGs) are a major component of the
extracellular matrix in the central nervous system (CNS) and play critical role in the …

Background Chondroitin sulfate proteoglycan (CSPG) is a major component of the glial scar.
It is considered to be a major obstacle for central nervous system (CNS) recovery after injury …

Massey et al., for example, applied chondroitinase ABC, a chondroitin sulfate-degrading
enzyme, combined with neurotrophin-3 (NT-3), one of the neurotrophic factors, to the dorsal …