We present a robust microfluidic platform for the stable generation of multiple chemical
gradients simultaneously using in situ self-assembly of particles in microchannels. This …

A fundamental challenge to multiplexing microfluidic chemotaxis assays at scale is the
requirement for time-lapse imaging to continuously track migrating cells. Drug testing and …

Escherichia coli chemotactic motion in spatiotemporally varying environments is studied by
using a computational model based on a coarse-grained description of the intracellular …

This paper presents a modeling and experimental framework to characterize the chemotaxis
of Serratia marcescens (S. marcescens) relying on two-dimensional and three-dimensional …

Chemotaxis plays a fundamental role in immune defense and cancer metastasis.
Microfluidic devices are increasingly applied to studying chemotaxis, owing to their …

How motile bacteria navigate environmental chemical gradients has implications ranging
from health to climate science, but the underlying behavioral mechanisms are unknown for …

Studies of chemotactic cell migration rely heavily on various assay systems designed to
evaluate the ability of cells to move in response to attractant molecules. In particular, the …

To swim up gradients of nutrients, E. coli senses nutrient concentrations within its periplasm.
For small nutrient molecules, periplasmic concentrations typically match extracellular …

Bacterial cells navigate their environment by directing their movement along chemical
gradients. This process, known as chemotaxis, can promote the rapid expansion of bacterial …

Chemotropism is an essential response of organisms to external chemical gradients that
direct the growth of cells toward the gradient source. Chemotropic responses between …