New evidence linking obesity and food addiction
EC Cope, E Gould - Biological psychiatry, 2017 - biologicalpsychiatryjournal.com
Obesity rates have skyrocketed over the past few decades. In the United States,
approximately 35% of adults are now considered obese, with more than 60% categorized as …
approximately 35% of adults are now considered obese, with more than 60% categorized as …
Reward, dopamine and the control of food intake: implications for obesity
The ability to resist the urge to eat requires the proper functioning of neuronal circuits
involved in top-down control to oppose the conditioned responses that predict reward from …
involved in top-down control to oppose the conditioned responses that predict reward from …
Role of opiate peptides in regulating energy balance
The endogenous opioid system, initially characterized over 30 years ago, is a primary
example of a multifunctional neural system involved in a wide range of basic homeostatic …
example of a multifunctional neural system involved in a wide range of basic homeostatic …
From taste hedonics to motivational drive: central µ-opioid receptors and binge-eating behaviour
PJ Nathan, ET Bullmore - International Journal of …, 2009 - academic.oup.com
Endogenous opioids and µ-opioid receptors (MORs) have long been implicated in the
mechanism of appetite control and, in particular, hedonic processes associated with food …
mechanism of appetite control and, in particular, hedonic processes associated with food …
Principles of motivation revealed by the diverse functions of neuropharmacological and neuroanatomical substrates underlying feeding behavior
Circuits that participate in specific subcomponents of feeding (eg, gustatory perception,
peripheral feedback relevant to satiety and energy balance, reward coding, etc.) are found at …
peripheral feedback relevant to satiety and energy balance, reward coding, etc.) are found at …
Intake of high-fat food is selectively enhanced by muopioid receptor stimulation within the nucleus accumbens
M Zhang, BA Gosnell, AE Kelley - Journal of Pharmacology and …, 1998 - ASPET
The present study was designed to further investigate the nature of feeding induced by
opioid stimulation of the nucleus accumbens through an examination of the effects of intra …
opioid stimulation of the nucleus accumbens through an examination of the effects of intra …
Mu opioid receptor antagonism in the nucleus accumbens shell blocks consumption of a preferred sucrose solution in an anticipatory contrast paradigm
Y Katsuura, SA Taha - Neuroscience, 2014 - Elsevier
Binge eating, a central feature of multiple eating disorders, is characterized by excessive
consumption occurring during discrete, often brief, intervals. Highly palatable foods play an …
consumption occurring during discrete, often brief, intervals. Highly palatable foods play an …
Further developments in the neurobiology of food and addiction: update on the state of the science
Over the past three decades, obesity has become a major public health crisis in the United
States. The prevalence of obesity in the United States and in other parts of the world has led …
States. The prevalence of obesity in the United States and in other parts of the world has led …
Nucleus accumbens μ-opioids regulate intake of a high-fat diet via activation of a distributed brain network
MJ Will, EB Franzblau, AE Kelley - Journal of Neuroscience, 2003 - Soc Neuroscience
Endogenous opioid peptides within the nucleus accumbens, a forebrain site critical for the
regulation of reward-related behavior, are believed to play an important role in the control of …
regulation of reward-related behavior, are believed to play an important role in the control of …
Neurobiology of consummatory behavior: mechanisms underlying overeating and drug use
JR Barson, I Morganstern, SF Leibowitz - ILAR journal, 2012 - academic.oup.com
Consummatory behavior is driven by both caloric and emotional need, and a wide variety of
animal models have been useful in research on the systems that drive consumption of food …
animal models have been useful in research on the systems that drive consumption of food …