The present study was designed to further investigate the nature of feeding induced by
opioid stimulation of the nucleus accumbens through an examination of the effects of intra …

A large component of the evidence linking the endogenous opioid system to the control of
food intake and body weight has been derived from the ability of general and selective …

Endogenous opioid peptides within the nucleus accumbens, a forebrain site critical for the
regulation of reward-related behavior, are believed to play an important role in the control of …

To maintain constant body weight, an organism must be able to sense and counterbalance
different aspects of energy homeostasis including food intake, energy stores, and energy …

Opioid signaling has been strongly implicated in driving palatable food consumption. The
nucleus accumbens (NAcc) is one important site of this effect; hyperphagia elicited by …

The discovery of opiate receptors and endogenous opioid peptides within the central
nervous system has resulted in a number of speculations concerning the physiological …

There is evidence that endogenous opiates are involved in the control of feeding in
experimental animals. Several types of experimental obesity are associated with increased …

This paper summarizes efforts to identify structures involved in the opioid regulation of
feeding. Many opioid agonists and antagonists increase or decrease food intake when …

Endogenous opioid signaling contributes to the neural control of food intake. Opioid
signaling is thought to regulate palatability, the reward value of a food item as determined by …

There is evidence that opioids may affect food consumption through mechanisms as diverse
as reward or energy metabolism. However, these hypotheses are derived from studies …