Up-regulation of TLR9 gene expression by LPS in mouse macrophages via activation of NF-κB, ERK and p38 MAPK signal pathways

H An, H Xu, Y Yu, M Zhang, R Qi, X Yan, S Liu… - Immunology letters, 2002 - Elsevier
Toll-like receptors (TLR) are critical in the activation of macrophages by bacterial products. It
has been shown that TLR2 and TLR4 mediate lipopolysaccharide (LPS) and lipoproteins …

[HTML][HTML] NF-κB inhibition attenuates LPS-induced TLR4 activation in monocyte cells

J Wan, Y Shan, Y Fan, C Fan… - Molecular …, 2016 - spandidos-publications.com
Toll-like receptor (TLR) family are receptors for extracellular or intracellular signaling, such
as lipopolysaccharide (LPS), or 12-O-tetradecanoylphorbol-13-acetate. TLR induces the …

Gene expressions of Toll-like receptor 2, but not Toll-like receptor 4, is induced by LPS and inflammatory cytokines in mouse macrophages

T Matsuguchi, T Musikacharoen, T Ogawa… - The Journal of …, 2000 - journals.aai.org
Toll-like receptors (TLRs) are a family of mammalian homologues of Drosophila Toll and
play important roles in host defense. Two of the TLRs, TLR2 and TLR4, mediate the …

[HTML][HTML] Transcriptional regulation of the novel Toll-like receptor Tlr13

Z Shi, Z Cai, S Wen, C Chen, C Gendron… - Journal of Biological …, 2009 - ASBMB
Little has been known about Tlr13 (Toll-like receptor 13), a novel member of the Toll-like
receptor family. To elucidate the molecular basis of murine Tlr13 gene expression, the …

Involvement of ERK, p38 and NF‐κB signal transduction in regulation of TLR2, TLR4 and TLR9 gene expression induced by lipopolysaccharide in mouse dendritic …

H An, Y Yu, M Zhang, H Xu, R Qi, X Yan, S Liu… - …, 2002 - Wiley Online Library
Toll‐like receptors (TLR) are sentinel receptors capable of recognizing pathogen‐
associated molecule patterns (PAMP) such as lipopolysaccharide (LPS) and CpG …

TLR10 is a negative regulator of both MyD88-dependent and-independent TLR signaling

S Jiang, X Li, NJ Hess, Y Guan… - The Journal of …, 2016 - journals.aai.org
TLRs are central components of the innate immune system which, upon recognition of
bacterial, fungal or viral components, activate intracellular signals that lead to protective …

Endotoxin and cytokine regulation of toll-like receptor (TLR) 2 and TLR4 gene expression in murine liver and hepatocytes

T Matsumura, A Ito, T Takii, H Hayashi… - Journal of Interferon & …, 2000 - liebertpub.com
Toll-like receptor (TLR) 2 and TLR4 are members of the interleukin-1 receptor (IL-1R) family
and transduce similar signals as IL-1R in response to bacteria and bacterial components. In …

NF-κB and STAT5 play important roles in the regulation of mouse Toll-like receptor 2 gene expression

T Musikacharoen, T Matsuguchi, T Kikuchi… - The Journal of …, 2001 - journals.aai.org
Abstract Toll-like receptor 2 (TLR2) is involved in the innate immunity by recognizing various
bacterial components. We have previously reported that TLR2 gene expression is rapidly …

TLR9 ligand enhances proliferation of rat CD4+ T cell and modulates suppressive activity mediated by CD4+ CD25+ T cell

E Chiffoleau, JM Heslan, M Heslan… - International …, 2007 - academic.oup.com
Toll-like receptors (TLRs) play a crucial role in the initiation of innate responses following
microbial infection and also in adaptive immune responses by orchestrating the activation of …

Cutting edge: naturally occurring soluble form of mouse Toll-like receptor 4 inhibits lipopolysaccharide signaling

K Iwami, T Matsuguchi, A Masuda, T Kikuchi… - The Journal of …, 2000 - journals.aai.org
Toll-like receptors (TLRs) are a family of proteins playing important roles in host defense.
Mice defective of functional TLR4 are hyporesponsive to LPS, suggesting that TLR4 is …