Mechanisms of M. tuberculosis immune evasion as challenges to TB vaccine design
JD Ernst - Cell host & microbe, 2018 - cell.com
Tuberculosis (TB) is a large global health problem, in part because of the long period of
coevolution of the pathogen, Mycobacterium tuberculosis, and its human host. A major factor …
coevolution of the pathogen, Mycobacterium tuberculosis, and its human host. A major factor …
Immunology of Mycobacterium tuberculosis Infections
JK Sia, J Rengarajan - Microbiology spectrum, 2019 - Am Soc Microbiol
Tuberculosis (TB) is a serious global public health challenge that results in significant
morbidity and mortality worldwide. TB is caused by infection with the bacilli Mycobacterium …
morbidity and mortality worldwide. TB is caused by infection with the bacilli Mycobacterium …
The current status, challenges, and future developments of new tuberculosis vaccines
W Gong, Y Liang, X Wu - Human vaccines & immunotherapeutics, 2018 - Taylor & Francis
Mycobacterium tuberculosis complex causes tuberculosis (TB), one of the top 10 causes of
death worldwide. TB results in more fatalities than multi-drug resistant (MDR) HIV strain …
death worldwide. TB results in more fatalities than multi-drug resistant (MDR) HIV strain …
Antibody-mediated immunity against tuberculosis: implications for vaccine development
JM Achkar, A Casadevall - Cell host & microbe, 2013 - cell.com
There is an urgent need for new and better vaccines against tuberculosis (TB). Current
vaccine design strategies are generally focused on the enhancement of cell-mediated …
vaccine design strategies are generally focused on the enhancement of cell-mediated …
Interaction of Mycobacterium tuberculosis with the host: consequences for vaccine development
JES Dietrich, TM Doherty - Apmis, 2009 - Wiley Online Library
Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), remains a major
worldwide health problem that causes more than 2 million deaths annually. In addition, an …
worldwide health problem that causes more than 2 million deaths annually. In addition, an …
Future vaccination strategies against tuberculosis: thinking outside the box
SHE Kaufmann - Immunity, 2010 - cell.com
With almost a dozen vaccine candidates in clinical trials, tuberculosis (TB) research and
development is finally reaping the first fruits of its labors. Vaccine candidates in clinical trials …
development is finally reaping the first fruits of its labors. Vaccine candidates in clinical trials …
Tuberculosis vaccines and prevention of infection
TR Hawn, TA Day, TJ Scriba, M Hatherill… - Microbiology and …, 2014 - Am Soc Microbiol
Tuberculosis (TB) is a leading cause of death worldwide despite the availability of effective
chemotherapy for over 60 years. Although Mycobacterium bovis bacillus Calmette-Guérin …
chemotherapy for over 60 years. Although Mycobacterium bovis bacillus Calmette-Guérin …
Tuberculosis vaccine development: strength lies in tenacity
SHE Kaufmann - Trends in immunology, 2012 - cell.com
The past decade has witnessed a tremendous increase in the development of novel
vaccines against tuberculosis (TB). In mice, each of these vaccine candidates stimulates an …
vaccines against tuberculosis (TB). In mice, each of these vaccine candidates stimulates an …
Understanding and overcoming the barriers to T cell-mediated immunity against tuberculosis
KB Urdahl - Seminars in immunology, 2014 - Elsevier
Despite the overwhelming success of immunization in reducing, and even eliminating, the
global threats posed by a wide spectrum of infectious diseases, attempts to do the same for …
global threats posed by a wide spectrum of infectious diseases, attempts to do the same for …
Research advances for virus-vectored tuberculosis vaccines and latest findings on tuberculosis vaccine development
Z Hu, SH Lu, DB Lowrie, XY Fan - Frontiers in Immunology, 2022 - frontiersin.org
Tuberculosis (TB), caused by respiratory infection with Mycobacterium tuberculosis, remains
a major global health threat. The only licensed TB vaccine, the one-hundred-year-old Bacille …
a major global health threat. The only licensed TB vaccine, the one-hundred-year-old Bacille …