Recent advances in polymer microneedles for drug transdermal delivery: Design strategies and applications

R Wang, G Jiang, UE Aharodnikau… - Macromolecular …, 2022 - Wiley Online Library
In recent years, transdermal drug delivery based on microneedles (MNs) technology has
received extensive attention, which offers a safer and painless alternative to hypodermic …

Transdermal microneedles—a materials perspective

R Ali, P Mehta, MS Arshad, I Kucuk, MW Chang… - Aaps Pharmscitech, 2020 - Springer
Transdermal drug delivery is an emerging field in the pharmaceutical remit compared with
conventional methods (oral and parenteral). Microneedle (MN)-based devices have gained …

Microneedles: A versatile strategy for transdermal delivery of biological molecules

DJ Lim, JB Vines, H Park, SH Lee - International journal of biological …, 2018 - Elsevier
Human skin is made up of multiple layers and is designed to protect the human body. The
stratum corneum (SC), specifically, is a keratinized layer of skin through which molecules …

Microneedle-based drug delivery systems: microfabrication, drug delivery, and safety

RF Donnelly, TRR Singh, AD Woolfson - Drug delivery, 2010 - Taylor & Francis
Many promising therapeutic agents are limited by their inability to reach the systemic
circulation, due to the excellent barrier properties of biological membranes, such as the …

[HTML][HTML] Microneedle arrays combined with nanomedicine approaches for transdermal delivery of therapeutics

V Alimardani, SS Abolmaali, G Yousefi… - Journal of Clinical …, 2021 - mdpi.com
Organic and inorganic nanoparticles (NPs) have shown promising outcomes in transdermal
drug delivery. NPs can not only enhance the skin penetration of small/biomacromolecule …

Microneedles: an emerging transdermal drug delivery system

SH Bariya, MC Gohel, TA Mehta… - Journal of Pharmacy …, 2012 - academic.oup.com
Objectives One of the thrust areas in drug delivery research is transdermal drug delivery
systems (TDDS) due to their characteristic advantages over oral and parenteral drug …

Advances in microneedle-based transdermal delivery for drugs and peptides

K Aich, T Singh, S Dang - Drug Delivery and Translational Research, 2022 - Springer
Transdermal drug delivery is a viable and clinically proven route of administration. This route
specifically requires overcoming the mechanical barrier provided by the Stratum Corneum of …

[HTML][HTML] Microneedles in drug delivery: progress and challenges

M Avcil, A Çelik - Micromachines, 2021 - mdpi.com
In recent years, an innovative transdermal delivery technology has attracted great interest for
its ability to distribute therapeutics and cosmeceuticals for several applications, including …

Microneedles for drug delivery: trends and progress

K Cheung, DB Das - Drug delivery, 2016 - Taylor & Francis
In recent years, there has been a surge in the research and development of microneedles
(MNs), a transdermal delivery system that combines the technology of transdermal patches …

Microneedle array systems for long-acting drug delivery

LK Vora, K Moffatt, IA Tekko, AJ Paredes… - European Journal of …, 2021 - Elsevier
The development of microneedles (MNs) assisted drug delivery technologies have been
highly active for more than two decades. The minimally invasive and self-administered MN …