Microneedles: a new frontier in nanomedicine delivery

E Larrañeta, MTC McCrudden, AJ Courtenay… - Pharmaceutical …, 2016 - Springer
This review aims to concisely chart the development of two individual research fields,
namely nanomedicines, with specific emphasis on nanoparticles (NP) and microparticles …

Transdermal drug delivery system through polymeric microneedle: A recent update

M Azmana, S Mahmood, AR Hilles, UK Mandal… - Journal of Drug Delivery …, 2020 - Elsevier
As non-toxic, biodegradable, biocompatible materials, the polymeric microneedles have a
great significance in terms of delivering therapeutic drug molecules through the skin. They …

Intracorneal injection of a detachable hybrid microneedle for sustained drug delivery

KJ Lee, HB Song, W Cho, JH Kim, JH Kim, WH Ryu - Acta biomaterialia, 2018 - Elsevier
There are increasing demands for long-term and controlled corneal drug delivery to treat
various ocular diseases. Although biodegradable ocular inserts or contact lenses have been …

The progress of fabrication designs of polymeric microneedles and related biomedical applications

X Jiang, W Zhang, R Terry, W Li - BMEMat, 2023 - Wiley Online Library
Microneedles (MNs) have been broadly used for transdermal delivery of a variety of drugs,
ranging from small chemicals to biological macromolecules, due to the properties of …

Microneedle technologies for (trans) dermal drug and vaccine delivery

K Van Der Maaden, W Jiskoot, J Bouwstra - Journal of controlled release, 2012 - Elsevier
Microneedles have been used for the dermal and transdermal delivery of a broad range of
drugs, such as small molecular weight drugs, oligonucleotides, DNA, peptides, proteins and …

Design principles of microneedles for drug delivery and sampling applications

Z Le, J Yu, YJ Quek, B Bai, X Li, Y Shou, B Myint, C Xu… - Materials Today, 2023 - Elsevier
Microneedles technology is a powerful platform to achieve efficient transdermal delivery of
bioactive molecules for local or systemic therapies attributing to their minimally invasive …

Biomedical applications of microneedles in therapeutics: recent advancements and implications in drug delivery

NS Rejinold, JH Shin, HY Seok… - Expert opinion on drug …, 2016 - Taylor & Francis
Introduction: The skin, as the largest organ, is a better option for drug delivery in many
diseases. However, most transdermal delivery is difficult due to the low permeability of …

Dissolving polymeric microneedle arrays for electrically assisted transdermal drug delivery

MJ Garland, E Caffarel–Salvador, K Migalska… - Journal of controlled …, 2012 - Elsevier
It has recently been proposed that the combination of skin barrier impairment using
microneedles (MNs) coupled with iontophoresis (ITP) may broaden the range of drugs …

Hollow microneedles: A perspective in biomedical applications

Á Cárcamo-Martínez, B Mallon… - International journal of …, 2021 - Elsevier
Microneedles (MN) have the potential to become a highly progressive device for both drug
delivery and monitoring purposes as they penetrate the skin and pierce the stratum corneum …

The promise of microneedle technologies for drug delivery

RF Donnelly, MR Prausnitz - Drug Delivery and Translational Research, 2024 - Springer
Microneedle (MN) technologies offer the opportunity to improve patient access and target
delivery of drugs and vaccines to specific tissues. When in the form of skin patches, MNs can …