The CXC chemokine ligand (CXCL) 1 and its receptor CXC chemokine receptor (CXCR) 2
are widely expressed in the peripheral nervous systems (PNS) and central nervous systems …

Background: Neurological diseases have become an obvious challenge due to insufficient
therapeutic intervention. Therefore, novel drugs for various neurological disorders are in …

The aim of this review is to present data from the available literature concerning CXCL9,
CXCL10 and CXCL11, as well as their receptor 3 (CXCR3) in selected diseases of the …

M. Müller, S. Carter, MJ Hofer and IL Campbell (2010) Neuropathology and Applied
Neurobiology36, 368–387 The chemokine receptor CXCR3 and its ligands CXCL9 …

The central nervous system (CNS) is a highly complex tissue that is vital for a large number
of life-dependent processes. The neurons of the CNS are post-mitotic and cannot be easily …

Signaling through chemokine receptor CXCR3 in the brain has been implicated in various
brain diseases, as CXCR3 and its ligands are found under these conditions. Recently, a …

The innate immune system is a crucial component of inflammatory reactions, while the
central nervous system (CNS) is the most vulnerable site of the body to inflammatory tissue …

CXC chemokine receptor type 4 (CXCR4) is highly expressed in Parkinson's disease (PD)
mice's brains and is related to astrocyte signaling and microglial activation. This makes …

Inflammation within the central nervous system (CNS) is strictly controlled and if possible
prevented. Such a tight control is necessary due to high sensitivity of nervous tissue to …

Chemokines are small proinflammatory cytokines that possess the ability to stimulate
migration of inflammatory cells towards the tissue site of inflammation. Previous reports …