Background Alzheimer's disease (AD) is a complex multifactorial neurodegenerative
disorder and the most common form of dementia. AD is highly heritable, with heritability …

The integration of quantitative trait loci (QTL) with disease genome-wide association studies
(GWAS) has proven successful at prioritizing candidate genes at disease-associated loci …

Alzheimer's disease (AD) is a clinically heterogeneous neurodegenerative disease with a
strong genetic component. Several genes have been associated with AD risk for nearly 20 …

For two decades the search for genes involved in A lzheimer's disease brought little reward;
it was not until the advent of genome‐wide association studies (GWAS) that genetic …

Alzheimer's disease (AD) is a complex and multifactorial neurodegenerative disease. Due to
its long clinical course and lack of an effective treatment, AD has become a major public …

Neurodegenerative diseases (NDDs) like Alzheimer's disease (AD), Parkinson's disease
(PD), and amyotrophic lateral sclerosis (ALS) are defined by a myriad of complex …

Deciphering the genetic landscape of Alzheimer's disease (AD) is essential to define the
pathophysiological pathways involved and to successfully translate genomics to potential …

Aging is considered as one of the main factors promoting the risk for Parkinson's disease
(PD), and common mechanisms of dopamine neuron degeneration in aging and PD have …

Alzheimer's disease (AD) is a sporadic, chronic neurodegenerative disease, usually
occurring late in life. The last decade has witnessed tremendous advances in our …

As the size of genome-wide association studies increase, the number of associated trait loci
identified inevitably increase. One welcomes this if it allows the better delineation of the …