[HTML][HTML] Fused tricyclic guanidine alkaloids: Insights into their structure, synthesis and bioactivity

NZ Abd Rani, YK Lee, S Ahmad, R Meesala, I Abdullah - Marine Drugs, 2022 - mdpi.com
A marine natural product possesses a diverse and unique scaffold that contributes to a vast
array of bioactivities. Tricyclic guanidine alkaloids are a type of scaffold found only in marine …

[HTML][HTML] Recent advances in the isolation, synthesis and biological activity of marine guanidine alkaloids

J Liu, XW Li, YW Guo - Marine Drugs, 2017 - mdpi.com
Marine organisms are prolific resources of guanidine-containing natural products with
intriguing structures and promising biological activities. These molecules have therefore …

Structure, synthesis and biological properties of the pentacyclic guanidinium alkaloids

Y Shi, Y Moazami, JG Pierce - Bioorganic & medicinal chemistry, 2017 - Elsevier
The pentacyclic guanidinium alkaloids (PGAs) are a family of marine natural products that
possess a polycyclic guanidine-containing core and a long alkyl chain tethered spermidine …

Synthesis of marine guanidine alkaloids and their application as chemical/biological tools

K Nagasawa, Y Hashimoto - The Chemical Record, 2003 - Wiley Online Library
Ptilomycalin A and crambescidins, novel marine guanidine alkaloids, have a unique
pentacyclic guanidine structure, and exhibit a considerable array of biological activities. The …

The chemistry and biology of guanidine secondary metabolites

RGS Berlinck, DI Bernardi, T Fill… - Natural Product …, 2021 - pubs.rsc.org
Covering: 2017–2019 Guanidine natural products isolated from microorganisms, marine
invertebrates and terrestrial plants, amphibians and spiders, represented by non-ribosomal …

[HTML][HTML] Polycyclic guanidine alkaloids from Poecilosclerida marine sponges

E Sfecci, T Lacour, P Amade, M Mehiri - Marine drugs, 2016 - mdpi.com
Sessile marine sponges provide an abundance of unique and diversified scaffolds. In
particular, marine guanidine alkaloids display a very wide range of biological applications. A …

Short‐Cut Bio‐Inspired Synthesis of Tricyclic Guanidinic Motifs of Crambescidins and Batzelladines Marine Alkaloids

A El‐Demerdash, L Ermolenko, E Gros… - European Journal of …, 2020 - Wiley Online Library
We report a convenient short synthesis of tricyclic guanidine‐containing natural products
model featuring four‐component reaction between 2, 5‐dimethoxytetrahydrofuran, 2 …

The chemistry and biology of organic guanidine derivatives

RGS Berlinck, ACB Burtoloso… - Natural Product …, 2010 - pubs.rsc.org
Covering: 2008 and 2009. Previous review: Nat. Prod. Rep., 2008, 25, 919 Organic
guanidine compounds are reviewed, with emphasis on natural product isolation …

Natural guanidine derivatives

RGS Berlinck, MH Kossuga - Natural Product Reports, 2005 - pubs.rsc.org
Covering: 2002 to 2004. Previous review: Nat. Prod. Rep., 2002, 19, 617–649The literature
on guanidine-bearing natural products is reviewed, with emphasis on occurrence, isolation …

The chemistry and biology of organic guanidine derivatives

RGS Berlinck, ACB Burtoloso, MH Kossuga - Natural Product Reports, 2008 - pubs.rsc.org
Covering: 2005 to 2007. Previous review: Nat. Prod. Rep., 2005, 22, 516. Organic guanidine
compounds are reviewed, with emphasis on natural products isolation, identification …