Th17 cells in autoimmune demyelinating disease
BM Segal - Seminars in immunopathology, 2010 - Springer
Recently published studies in multiple sclerosis (MS) and experimental autoimmune
encephalomyelitis (EAE) have demonstrated an association between the development of …
encephalomyelitis (EAE) have demonstrated an association between the development of …
IL-17 and related cytokines involved in the pathology and immunotherapy of multiple sclerosis: current and future developments
DW Luchtman, E Ellwardt, C Larochelle… - Cytokine & growth factor …, 2014 - Elsevier
Multiple sclerosis (MS), an autoimmune neurological disorder, is driven by self-reactive T
helper (Th) cells. Research on the role of Th17 lymphocytes in MS pathogenesis has made …
helper (Th) cells. Research on the role of Th17 lymphocytes in MS pathogenesis has made …
The role of TH17 cells in multiple sclerosis: Therapeutic implications
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system (CNS) where immunopathology is thought to be mediated by myelin-reactive CD4+ T …
system (CNS) where immunopathology is thought to be mediated by myelin-reactive CD4+ T …
IL-17A and multiple sclerosis: signaling pathways, producing cells and target cells in the central nervous system
F Kolbinger, C Huppertz, A Mir… - Current Drug …, 2016 - ingentaconnect.com
Multiple sclerosis (MS) is an immune mediated demyelinating disease of the central nervous
system (CNS). The importance of immune cells to MS pathology is supported by clinical data …
system (CNS). The importance of immune cells to MS pathology is supported by clinical data …
TH17 cytokines in autoimmune neuro-inflammation
B Becher, BM Segal - Current opinion in immunology, 2011 - Elsevier
It has been firmly established that IL-23 polarized TH17 cells are potent effectors in the
pathogenesis of experimental autoimmune encephalitomyelitis (EAE). However, the relative …
pathogenesis of experimental autoimmune encephalitomyelitis (EAE). However, the relative …
IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis
S Serada, M Fujimoto, M Mihara… - Proceedings of the …, 2008 - National Acad Sciences
The development of Th17 cells is a key event in the pathogenesis of experimental
autoimmune encephalomyelitis (EAE), a murine model of human multiple sclerosis (MS) …
autoimmune encephalomyelitis (EAE), a murine model of human multiple sclerosis (MS) …
Current views on the roles of Th1 and Th17 cells in experimental autoimmune encephalomyelitis
Multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis
(EAE), are autoimmune demyelinating diseases of the central nervous system (CNS) …
(EAE), are autoimmune demyelinating diseases of the central nervous system (CNS) …
Phenotypical and functional characterization of T helper 17 cells in multiple sclerosis
V Brucklacher-Waldert, K Stuerner, M Kolster… - Brain, 2009 - academic.oup.com
Multiple sclerosis is a T cell-mediated demyelinating disease of the central nervous system.
Interleukin-17-producing T helper cells, named Th17 cells, represent a novel CD4+ T cell …
Interleukin-17-producing T helper cells, named Th17 cells, represent a novel CD4+ T cell …
Th17 cells, γδ T cells and their interplay in EAE and multiple sclerosis
AM McGinley, SC Edwards, M Raverdeau… - Journal of …, 2018 - Elsevier
Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis
(MS) that shares many features with the human disease. This review will focus on the role of …
(MS) that shares many features with the human disease. This review will focus on the role of …
The interleukin (IL)-23/T helper (Th) 17 axis in experimental autoimmune encephalomyelitis and multiple sclerosis
M Hiltensperger, T Korn - Cold Spring …, 2018 - perspectivesinmedicine.cshlp.org
T helper (Th) 17 cells are responsible for host defense against fungi and certain extracellular
bacteria but have also been reported to play a role in a variety of autoimmune diseases …
bacteria but have also been reported to play a role in a variety of autoimmune diseases …