Background Tuberculosis (TB) control is hindered by absence of rapid tests to identify
Mycobacterium tuberculosis (MTB) and detect isoniazid (INH) and rifampin (RIF) resistance …

With increasing incidence of multidrug-resistant tuberculosis (MDR-TB), accurate drug
susceptibility testing (DST) of Mycobacterium tuberculosis to first-line drugs has become …

Objectives Multidrug-resistant tuberculosis has emerged as a global health threat. Given
poor treatment outcomes of fluoroquinolone-resistant multidrug-resistant tuberculosis, there …

Background Genotypic (molecular) methods have considerable advantages for scaling up
programmatic management and surveillance of drug-resistant tuberculosis (TB), offering …

The global extensively drug-resistant tuberculosis (TB) response plan calls for
implementation of rapid tests to screen patients at risk of drug-resistant TB. Currently, two …

Despite numerous intervention strategies, including the direct observed short-course
treatment strategy and improved diagnostic methods, the incidence of multidrug-resistant …

Increasingly complex drug-resistant tuberculosis (DR-TB) is a major global health concern
and one of the primary reasons why TB is now the leading infectious cause of death …

Summary Background The Xpert MTB/RIF test (Cepheid, Sunnyvale, CA, USA) can detect
tuberculosis and its multidrug-resistant form with very high sensitivity and specificity in …

We surveyed availability of phenotypic drug susceptibility testing for drug-resistant
Mycobacterium tuberculosis in Europe. Of 27 laboratories, 17 tested for linezolid, 11 for …

We present a statistical summary of results from the Model Performance Evaluation Program
(MPEP) for Mycobacterium tuberculosis Drug Susceptibility Testing, 1994 to 2008 …