The toxicity of aminoglycosides including gentamicin (GEN), the most widely used drug in
this category, is believed to be related to the generation of reactive oxygen species (ROS) in …

Aminoglycoside antibiotics have long been used in antibacterial therapy. Despite their
beneficial effects, aminoglycosides have considerable nephrotoxic and ototoxic side effects …

Gentamicin (GM) is used against serious and life‐threatening infections, but its use is limited
by the occurrence of nephrotoxicity, which involves the generation of free radicals. In this …

The toxicity of gentamicin (GEN) in the kidney seems to relate to the generation of reactive
oxygen species (ROS). Caffeic acid phenethyl ester (CAPE) has been demonstrated to have …

Gentamicin (GM) is an effective aminoglycoside antibiotic against life‐threatening Gram‐
negative bacteria. However, a major complication of therapeutic doses of GM is …

Gentamicin (GM) is a widely used antibiotic against serious and life‐threatening infections,
but its usefulness is limited by the development of nephrotoxicity. The present study was …

Reactive oxygen species are involved in gentamicin (GM) nephrotoxicity, and garlic is
effective in preventing or ameliorating oxidative stress. Therefore, the effect of garlic on GM …

Background: Gentamicin is very useful aminoglycoside in treatment of gram negative
organisms but nephrotoxicity has been a major limiting factor. Various renal pathologies …

Gentamicin-induced nephrotoxicity has been well documented, although its underlying
mechanisms and preventive strategies remain to be investigated. The present study was …

Gentamicin is an effective widely used antibiotic, but the risk of nephrotoxicity and oxidative
damage limit its long-term use. Hence, the current study aims to elucidate such hazardous …