The prevalence of obesity has markedly increased over the past two decades, especially in
the industrialized countries. While the impact of excess body weight on the development of …

Obesity, defined as the abnormal or excessive expansion of white adipose tissue, has
reached pandemic proportions and is recognized as an important health concern since it is …

The adipocyte-released hormone-like cytokine/adipokine leptin behaves differently in
obesity compared to its functions in the normal healthy state. In obese individuals, elevated …

Leptin is an obesity-associated adipokine that is known to regulate energy metabolism and
reproduction and to control appetite via the leptin receptor. Recent work has identified …

Obesity is a well‐established risk factor for the development and mortality from several
cancers, including adenocarcinoma of the oesophagus, oesophago‐gastric junction and …

Significant correlations between obesity and incidence of various cancers have been
reported. Obesity, considered a mild inflammatory process, is characterized by a high level …

Leptin is an important regulator of basal metabolism and food intake, with a pivotal role in
obesity. Leptin exerts many different actions on various tissues and systems, including …

Obesity is a new risk factor, to which more and more research is devoted, related to the
development of cancer. Many studies of recent years have drawn attention to the role of …

Background & Aims: Obesity increases the risk of colon cancer, whereas physical activity
reduces the risk. Plasma levels of leptin increase in proportion to the level of obesity and are …

Obesity is a risk factor of breast cancers. As leptin, a hormone mainly secreted by white
adipocytes, elicits proliferative effects in some cell types, we tested the hypothesis that leptin …