[HTML][HTML] Phenotype changes and impaired function of dendritic cell subsets in patients with sepsis: a prospective observational analysis
H Poehlmann, JC Schefold, H Zuckermann-Becker… - Critical care, 2009 - Springer
Introduction Patients with sepsis often demonstrate severely impaired immune responses.
The hallmark of this state of immunoparalysis is monocytic deactivation characterized by …
The hallmark of this state of immunoparalysis is monocytic deactivation characterized by …
[HTML][HTML] Causes of death and determinants of outcome in critically ill patients
VD Mayr, MW Dünser, V Greil, S Jochberger… - Critical care, 2006 - Springer
Introduction Whereas most studies focus on laboratory and clinical research, little is known
about the causes of death and risk factors for death in critically ill patients. Methods Three …
about the causes of death and risk factors for death in critically ill patients. Methods Three …
[HTML][HTML] Effects of changes in arterial pressure on organ perfusion during septic shock
A Thooft, R Favory, DR Salgado, FS Taccone… - Critical Care, 2011 - Springer
Introduction Septic shock is characterized by altered tissue perfusion associated with
persistent arterial hypotension. Vasopressor therapy is generally required to restore organ …
persistent arterial hypotension. Vasopressor therapy is generally required to restore organ …
[HTML][HTML] Matrix metalloproteinase-9,-10, and tissue inhibitor of matrix metalloproteinases-1 blood levels as biomarkers of severity and mortality in sepsis
L Lorente, MM Martín, L Labarta, C Díaz, J Solé-Violán… - Critical care, 2009 - Springer
Abstract Introduction Matrix metalloproteinases (MMPs) play a role in infectious diseases
through extracellular matrix (ECM) degradation, which favors the migration of immune cells …
through extracellular matrix (ECM) degradation, which favors the migration of immune cells …
[HTML][HTML] Temporal patterns of organ dysfunction after severe trauma
J Eriksson, D Nelson, A Holst, E Hellgren, O Friman… - Critical Care, 2021 - Springer
Background Understanding temporal patterns of organ dysfunction (OD) may aid early
recognition of complications after trauma and assist timing and modality of treatment …
recognition of complications after trauma and assist timing and modality of treatment …
[HTML][HTML] DHEA-dependent and organ-specific regulation of TNF-α mRNA expression in a murine polymicrobial sepsis and trauma model
T Barkhausen, F Hildebrand, C Krettek… - Critical Care, 2009 - Springer
Introduction Dehydroepiandrosterone (DHEA) improves survival after trauma and sepsis,
while mechanisms of action are not yet fully understood. Therefore, we investigated the …
while mechanisms of action are not yet fully understood. Therefore, we investigated the …
[HTML][HTML] Paradoxical response to chest wall loading predicts a favorable mechanical response to reduction in tidal volume or PEEP
Background Chest wall loading has been shown to paradoxically improve respiratory
system compliance (CRS) in patients with moderate to severe acute respiratory distress …
system compliance (CRS) in patients with moderate to severe acute respiratory distress …
[HTML][HTML] Soluble programmed cell death protein-1 and programmed cell death ligand-1 in sepsis
D Banerjee, S Monaghan, R Zhao, T Walsh… - Critical Care, 2018 - Springer
Immunotherapy targeting the programmed cell death protein-1 (PD-1)–programmed cell
death ligand-1 (PDL-1) axis in sepsis is poised for clinical trials, although optimal inclusion …
death ligand-1 (PDL-1) axis in sepsis is poised for clinical trials, although optimal inclusion …
[HTML][HTML] Postoperative blood pressure deficit and acute kidney injury progression in vasopressor-dependent cardiovascular surgery patients
S Saito, S Uchino, M Takinami, S Uezono, R Bellomo - Critical Care, 2016 - Springer
Background In vasopressor-dependent patients who had undergone cardiovascular
surgery, we examined whether those with progression of acute kidney injury (AKI) had a …
surgery, we examined whether those with progression of acute kidney injury (AKI) had a …
[HTML][HTML] Performance comparison of ventricular and arterial dP/dtmax for assessing left ventricular systolic function during different experimental loading and …
MI Monge Garcia, Z Jian, JJ Settels, C Hunley… - Critical Care, 2018 - Springer
Background Maximal left ventricular (LV) pressure rise (LV dP/dt max), a classical marker of
LV systolic function, requires LV catheterization, thus surrogate arterial pressure waveform …
LV systolic function, requires LV catheterization, thus surrogate arterial pressure waveform …