Macroautophagy and aging: The impact of cellular recycling on health and longevity
JL Nieto-Torres, M Hansen - Molecular aspects of medicine, 2021 - Elsevier
Aging is associated with many deleterious changes at the cellular level, including the
accumulation of potentially toxic components that can have devastating effects on health. A …
accumulation of potentially toxic components that can have devastating effects on health. A …
Autophagy and the cell biology of age-related disease
Macroautophagy (autophagy) is a conserved lysosomal degradation process essential for
cellular homeostasis and adaption to stress. Accumulating evidence indicates that …
cellular homeostasis and adaption to stress. Accumulating evidence indicates that …
Autophagy and the hallmarks of aging
Autophagy, an essential cellular process that mediates degradation of proteins and
organelles in lysosomes, has been tightly linked to cellular quality control for its role as part …
organelles in lysosomes, has been tightly linked to cellular quality control for its role as part …
Autophagy in healthy aging and disease
Autophagy is a fundamental cellular process that eliminates molecules and subcellular
elements, including nucleic acids, proteins, lipids and organelles, via lysosome-mediated …
elements, including nucleic acids, proteins, lipids and organelles, via lysosome-mediated …
Autophagy and ageing: implications for age-related neurodegenerative diseases
Autophagy is a process of lysosome-dependent intracellular degradation that participates in
the liberation of resources including amino acids and energy to maintain homoeostasis …
the liberation of resources including amino acids and energy to maintain homoeostasis …
Autophagy and aging
N Martinez-Lopez, D Athonvarangkul… - Longevity Genes: A …, 2015 - Springer
Autophagy is a critical quality control pathway that is conserved across diverse systems
ranging from simple unicellular organisms like yeast to more complex systems, for instance …
ranging from simple unicellular organisms like yeast to more complex systems, for instance …
Autophagy in aging and in neurodegenerative disorders
YS Rajawat, I Bossis - Hormones, 2008 - Springer
Autophagy (ATG) is the process of bulk degradation and recycling of long-lived proteins,
macromolecular aggregates, and damaged intracellular organelles. Cellular homeostasis …
macromolecular aggregates, and damaged intracellular organelles. Cellular homeostasis …
[HTML][HTML] Autophagy, cellular aging and age-related human diseases
SY Cheon, H Kim, DC Rubinsztein… - Experimental …, 2019 - ncbi.nlm.nih.gov
Macroautophagy/autophagy is a conserved degradation system that engulfs
intracytoplasmic contents, including aggregated proteins and organelles, which is crucial for …
intracytoplasmic contents, including aggregated proteins and organelles, which is crucial for …
Autophagy in aging and longevity
SQ Wong, AV Kumar, J Mills, LR Lapierre - Human genetics, 2020 - Springer
Our understanding of the process of autophagy and its role in health and diseases has
grown remarkably in the last two decades. Early work established autophagy as a general …
grown remarkably in the last two decades. Early work established autophagy as a general …
Autophagy and aging: Roles in skeletal muscle, eye, brain and hepatic tissue
P Li, Y Ma, C Yu, S Wu, K Wang, H Yi… - Frontiers in Cell and …, 2021 - frontiersin.org
Autophagy is an evolutionary conserved degradative process contributing to cytoplasm
quality control, metabolic recycling and cell defense. Aging is a universal phenomenon …
quality control, metabolic recycling and cell defense. Aging is a universal phenomenon …