Organoid technology holds great promise for regenerative medicine. Recent studies show
feasibility for bile duct tissue repair in humans by successfully transplanting cholangiocyte …

Human cholangiocyte organoids are promising for regenerative medicine applications, such
as repair of damaged bile ducts. However, organoids are typically cultured in mouse tumor …

Pediatric liver transplantation is often required as a consequence of biliary disorders
because of the lack of alternative treatments for repairing or replacing damaged bile ducts …

Organoid technology holds great promise for regenerative medicine but has not yet been
applied to humans. We address this challenge using cholangiocyte organoids in the context …

The well‐established 3D organoid culture method enabled efficient expansion of
cholangiocyte‐like cells from intrahepatic (IHBD) and extrahepatic bile duct (EHBD) tissue …

The burden of liver diseases is increasing worldwide, with liver transplantation remaining
the only treatment option for end‐stage liver disease. Regenerative medicine holds great …

Biliary disorders can lead to life‐threatening disease and are also a challenging
complication of liver transplantation. As there are limited treatment options, tissue …

Three-dimensional scaffolds decellularized from native organs are a promising technique to
establish engineered liver grafts and overcome the current shortage of donor organs …

Cholangiopathies, which affect extrahepatic bile ducts (EHBDs), include biliary atresia,
primary sclerosing cholangitis, and cholangiocarcinoma. They have no effective therapeutic …

Background Organoids, which enable disease modeling and drug screening closer to an in
vivo environment, can be isolated and grown from organs such as the brain, small intestine …