Screening and identification of hub genes in pancreatic cancer by integrated bioinformatics analysis

Q Chen, D Yu, Y Zhao, J Qiu, Y Xie… - Journal of Cellular …, 2019 - Wiley Online Library
Pancreatic cancer (Pa) is a malignant tumor of the digestive tract with high degree of
malignancy, this study aimed to obtain the hub genes in the tumorigenesis of Pa. Microarray …

[HTML][HTML] Identification of key candidate genes for pancreatic cancer by bioinformatics analysis

K Lv, J Yang, J Sun, J Guan - Experimental and …, 2019 - spandidos-publications.com
Although pancreatic cancer has the highest mortality rate among all neoplasms worldwide,
its exact mechanism remains poorly understood. In the present study, three Gene …

[HTML][HTML] Identification of hub genes with diagnostic values in pancreatic cancer by bioinformatics analyses and supervised learning methods

C Li, X Zeng, H Yu, Y Gu, W Zhang - World journal of surgical oncology, 2018 - Springer
Background Pancreatic cancer is one of the most lethal tumors with poor prognosis, and
lacks of effective biomarkers in diagnosis and treatment. The aim of this investigation was to …

[HTML][HTML] Identification of key genes and pathways in pancreatic cancer gene expression profile by integrative analysis

W Lu, N Li, F Liao - Genes, 2019 - mdpi.com
Background: Pancreatic cancer is one of the malignant tumors that threaten human health.
Methods: The gene expression profiles of GSE15471, GSE19650, GSE32676 and …

[HTML][HTML] Identification of prognostic risk factors for pancreatic cancer using bioinformatics analysis

D Jin, Y Jiao, J Ji, W Jiang, W Ni, Y Wu, R Ni, C Lu… - PeerJ, 2020 - peerj.com
Background Pancreatic cancer is one of the most common malignant cancers worldwide.
Currently, the pathogenesis of pancreatic cancer remains unclear; thus, it is necessary to …

Exploration and validation of pancreatic cancer hub genes based on weighted gene co-expression network analysis and immune infiltration score analysis

XX Li, H Li, LQ Jin, YB Tan - Pharmacogenomics and Personalized …, 2023 - Taylor & Francis
Objective To find pancreatic cancer (PC)-related hub genes based on weighted gene co-
expression network analysis (WGCNA) construction and immune infiltration score analysis …

Integrated bioinformatics analysis of potential biomarkers for pancreatic cancer

H Shi, H Xu, C Chai, Z Qin… - Journal of Clinical …, 2022 - Wiley Online Library
Background Pancreatic cancer, particularly pancreatic ductal adenocarcinoma (PDA), is an
aggressive malignancy associated with a low 5‐year survival rate. Poor outcomes …

Identification of hub genes and analysis of prognostic values in pancreatic ductal adenocarcinoma by integrated bioinformatics methods

Y Lu, C Li, H Chen, W Zhong - Molecular biology reports, 2018 - Springer
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers in the world,
and more molecular mechanisms should be illuminated to meet the urgent need of …

[HTML][HTML] Integrated transcriptomic analysis reveals hub genes involved in diagnosis and prognosis of pancreatic cancer

YY Zhou, LP Chen, Y Zhang, SK Hu, ZJ Dong, M Wu… - Molecular …, 2019 - Springer
Background The hunt for the molecular markers with specificity and sensitivity has been a
hot area for the tumor treatment. Due to the poor diagnosis and prognosis of pancreatic …

[HTML][HTML] Identification of hub genes and regulators associated with pancreatic ductal adenocarcinoma based on integrated gene expression profile analysis

M Shang, L Zhang, X Chen, S Zheng - Discovery Medicine, 2019 - discoverymedicine.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies without
effective screening strategy during the early stage. Therefore, a novel screening panel was …