Simple Summary Colorectal cancer is a leading cause of death worldwide. Despite the
development of novel surgical and therapeutic strategies, 50% of patients relapse after …

Colorectal cancer (CRC) is a prevalent and serious gastrointestinal malignancy with high
mortality and morbidity. Chemoprevention refers to a newly emerged strategy that uses …

Colorectal cancer (CRC) remains a major cause of cancer death worldwide. Over 70% of
CRC cases are sporadic and related to lifestyle. Epidemiological studies inversely correlate …

Polyphenols have been reported to have wide spectrum of biological activities including
major impact on initiation, promotion, and progression of cancer by modulating different …

Polyphenolic compounds, widely present in fruits, vegetables, and cereals, have potential
benefits for human health and are protective agents against the development of …

Colorectal cancer is one of the leading causes of premature death in people worldwide. Due
to the fact that malignant conversion of normal colonic cells requires several steps and often …

Although the chemoprevention and anti-cancer activities of dietary polyphenols have been
evidenced through both in vitro and in vivo studies, most of the human clinical trials were …

Current focus in colorectal cancer (CRC) management is on reducing overall mortality by
increasing the number of early-stage cancers diagnosed and treated with curative intent …

Colorectal cancer (CRC) is one of the most prevalent cancers that threaten people in many
countries. It is a multi-factorial chronic disease caused by a combination of genetic and …

Colon cancer commonly develops from long-term chronic inflammation in the intestine and
seriously threatens human health. Natural polyphenols have been valued as a crucial …