Differences in apolipoprotein (a) polymorphism in west Greenland Eskimos and Caucasian Danes

IC Klausen, LU Gerdes, EB Schmidt, J Dyerberg… - Human genetics, 1992 - Springer
Previous studies in Greenland suggest that death rates from ischemic heart disease [IHD]
are lower in Eskimos than in Danes and other Caucasian populations. This has been …

Predictors of plasma lipoprotein (a) concentration in the West of Scotland Coronary Prevention Study cohort

A Gaw, G Docherty, EA Brown, I Ford… - Atherosclerosis, 1999 - Elsevier
An elevated plasma lipoprotein (a)(Lp (a)) concentration is an independent risk factor for
coronary heart disease (CHD). Plasma Lp (a) levels are believed to be predominantly …

LPA gene: interaction between the apolipoprotein(a) size ('kringle IV' repeat) polymorphism and a pentanucleotide repeat polymorphism influences Lp(a) lipoprotein …

O Røsby, K Berg - Journal of internal medicine, 2000 - Wiley Online Library
Røsby O, Berg K (University of Oslo and Ullevål University Hospital, Oslo, Norway). LPA
gene: interaction between the apolipoprotein (a) size ('kringle IV'repeat) polymorphism and …

Structure, function, and genetics of lipoprotein (a)

K Schmidt, A Noureen, F Kronenberg… - Journal of lipid …, 2016 - ASBMB
Lipoprotein (a)[Lp (a)] has attracted the interest of researchers and physicians due to its
intriguing properties, including an intragenic multiallelic copy number variation in the LPA …

[PDF][PDF] Concentrations of the atherogenic Lp (a) are elevated in FH

A Lingenhel, HG Kraft, M Kotze, AV Peeters… - Eur J Hum …, 1998 - academia.edu
Lipoprotein (a)(Lp (a)) is a complex in human plasma assembled from lowdensity lipoprotein
(LDL) and apolipoprotein (a)(apo (a)). High plasma concentrations of Lp (a) are a risk factor …

Lp (a) concentrations are related to plasma lipid concentrations

DL Rainwater - Atherosclerosis, 1996 - Elsevier
Lp (a) concentrations are controlled primarily by genetic variation at LPA, the locus encoding
the unique protein apo (a). However, the high heritability is in part a consequence of nearly …

Lipoprotein (a) in homozygous familial hypercholesterolemia

HG Kraft, A Lingenhel, FJ Raal… - … , and vascular biology, 2000 - Am Heart Assoc
Lipoprotein (a)[Lp (a)] is a quantitative genetic trait that in the general population is largely
controlled by 1 major locus—the locus for the apolipoprotein (a)[apo (a)] gene. Sibpair …

Lipoprotein (a) concentrations, apolipoprotein (a) phenotypes, and peripheral arterial disease in three independent cohorts

A Laschkolnig, B Kollerits, C Lamina… - Cardiovascular …, 2014 - academic.oup.com
Aims The relevance of lipoprotein (a)[Lp (a)] concentrations and low-molecular-weight
(LMW) apo (a) phenotypes in peripheral arterial disease (PAD) has only been investigated …

Conventional and Mendelian randomization analyses suggest no association between lipoprotein (a) and early atherosclerosis: the Young Finns Study

M Kivimäki, CG Magnussen, M Juonala… - International journal …, 2011 - academic.oup.com
Abstract Background Lipoprotein (a)[Lp (a)] is an established risk factor for coronary disease
and stroke, but mechanisms underlying this association are unknown. We examined the …

Comprehensive Analysis of Genomic Variation in the LPA Locus and Its Relationship to Plasma Lipoprotein(a) in South Asians, Chinese, and European Caucasians

MB Lanktree, SS Anand, S Yusuf… - Circulation …, 2010 - Am Heart Assoc
Background—Functional copy number variation in the apolipoprotein (a) gene (LPA)
underlies a variable number of protein kringle domains repeated in tandem in the lipoprotein …