The development of blood vessels, referred to as angiogenesis, is an intricate process
regulated spatially and temporally through a delicate balance between the qualitative and …

Angiogenesis is indispensable for solid tumor expansion, and thus it has become a major
target of cancer research and anti-cancer therapies. Deciphering the arcane actions of …

The hallmark of tumours is the ability of cancerous cells to promote vascular growth, to
disseminate and invade to distant organs. The metastatic process is heavily influenced by …

Emerging evidence shows that endothelial cells are not only the building blocks of vascular
networks that enable oxygen and nutrient delivery throughout a tissue but also serve as a …

Glioblastoma (GBM) angiogenesis is critical for tumor growth and recurrence, making it a
compelling therapeutic target. Here, a disease-relevant, vascularized tumoroid in vitro model …

Cell–microenvironment interactions play a critical role in the transformation of normal cells
into cancer; however, the underlying mechanisms and effects are far from being well …

Tumor angiogenesis is a hallmark of cancer that has been identified as a critical component
of cancer progression, facilitating rapid tumor growth and metastasis. Anti-angiogenic …

The extracellular matrix interacts with cancer cells and is a key factor in the development of
cancer. Traditional two-dimensional models cannot mimic the natural in situ environment of …

Blood supply is essential for development and growth of tumors and angiogenesis is the
fundamental process of new blood vessel formation from preexisting ones. Angiogenesis is …

With greater technological advancements and understanding of pathophysiology,“
personalized medicine” has become a more realistic goal. In the field of cancer …