Introduction: Metastatic colorectal cancer (CRC) remains a dilemma for cancer researchers
with an increasing incidence in the younger patient population. Until the last decade, limited …

Colorectal cancer (CRC) represents approximately 10% of all cancers and is the second
most common cause of cancer deaths. Initial clinical presentation as metastatic CRC …

Simple Summary Metastatic colorectal cancer (mCRC) represents a significant burden in
cancer-related morbidity and mortality. The study of mCRC-related genetic alterations and …

Systemic therapeutic efficacy is central to determining the outcome of patients with
metastatic colorectal cancer (CRC). In these patients, there is a critical need for predictive …

Importance Colorectal cancer (CRC) is the third most common cause of cancer mortality
worldwide with more than 1.85 million cases and 850 000 deaths annually. Of new …

There have been substantial advances in the treatment of metastatic colorectal cancer
(mCRC) over the past 15 years. Molecular characteristics of mCRC and identification of …

Colorectal cancer (CRC) represents 10% of all cancer types, making it the third leading
cause of cancer-related deaths globally. Metastasis is the primary factor causing mortality in …

Colorectal cancer remains one of the most common cancers worldwide and is almost
uniformly fatal for those with metastatic disease. Despite this, there is an increasing number …

Introduction: Colorectal cancer (CRC) is one of the leading causes of cancer deaths
worldwide. Despite the introduction of several new drugs targeting the vascular endothelial …

The approval of targeted therapies for metastatic colorectal cancer (mCRC) has led to
important improvements in patient outcomes. However, it is still necessary to increase …