The therapeutic potential of targeting tumor endothelium and vascular supply is now widely
recognized to treat different diseases. One such disease is cancer; where endothelial cells …

Cancer is one of the leading causes of death in the Western world. Though advances in
cancer therapy and diagnosis have considerably improved life expectancy, the overall …

Targeting angiogenesis represents a new strategy for the development of anticancer
therapies. New targets derived from proliferating endothelial cells may be useful in …

Angiogenesis–the formation of new blood vessels within a tumor (or many other tissue
types)–has become a hotbed of pharmacological research as well as industrial drug …

Angiogenesis, or new blood vessel formation, is now known to play an important role in both
growth and metastasis of many cancers. The central importance of angiogenesis and the …

Background Angiogenesis, the formation of new blood vessels from the endothelium of the
existing vasculature, is fundamental in tumor growth, progression, and metastasis. Inhibiting …

Angiogenesis plays a crucial role in facilitating tumor growth and the metastatic process, and
it is the result of a dynamic balance between pro-angiogenic factors, like vascular …

Angiogenesis is a complex process depending on the coordination of many regulators and
there by activating angiogenic switch. Recent advances in understanding of angiogenic …

Tumor angiogenesis, the growth of new blood vessels into tumors, facilitates tumor growth
and thus represents an attractive therapeutic target. Numerous experimental angiogenesis …

The discovery of tumor angiogenesis opened a new path in fighting cancer. The approval of
different antiangiogenic agents, most targeting vascular endothelial growth factor (VEGF) …