Cytokines that control the immune response were shown to have efficacy in preclinical
murine cancer models. Interferon (IFN)-α is approved for treatment of hairy cell leukemia …

Cytokines are soluble proteins that mediate cell-to-cell communication. Based on the
discovery of the potent anti-tumour activities of several pro-inflammatory cytokines in animal …

The immune system plays a vital role in regulating the growth of tumors. Some types of
inflammatory responses can promote tumor growth, while a tumor-specific adaptive immune …

Cytokines are major regulators of innate and adaptive immunity that enable cells of the
immune system to communicate over short distances. Cytokine therapy to activate the …

Cancer immunotherapy has dramatically changed the approach to cancer treatment. The
aim of targeting the immune system to recognize and destroy cancer cells has afforded …

The immune system has the greatest potential for the specific destruction of tumours with no
toxicity to normal tissue and for long-term memory that can prevent cancer recurrence. The …

Cancer immunotherapy is an evolving field of research. Cytokines have been
conceptualized as an anticancer therapy for longer than most other cancer immunotherapy …

The recent clinical successes of immune checkpoint blockade and chimeric antigen receptor
T cell therapies represent a turning point in cancer immunotherapy. These successes also …

Immunotherapy strategies against cancer are emerging as powerful weapons for treatment
of this disease. The success of checkpoint inhibitors against metastatic melanoma and …

Recent success of immunotherapy strategies such as immune checkpoint blockade in
several malignancies has established the role of immunotherapy in the treatment of cancer …